Products

DermalRx® SRC-R (R10099) is a yeast-derived oligopeptide that promotes skin renewal by stimulating natural exfoliation via gentle and selective desquamation. Clinical testing demonstrates that DermalRx® SRC-R enhances exfoliation to reduce skin roughness and improve the appearance of wrinkles in four weeks. DermalRx® SRC-R gently loosens coarse keratinized cells at the surface, delivering results for applications in anti-aging, anti-wrinkle, anti-blemish, skin brightening, and exfoliation products. DermalRx® SRC-R is clinically demonstrated to restore skin texture and radiance with documented improvements in the appearance of hyperpigmentation, wrinkles, and other signs of aging. DermalRx® SRC-R is a selective exfoliant for safe, effective skin renewal.

Tellirictin® (R10047) is a proprietary clove flower extract containing natural gallate-based pleiotropic compounds (tellimagrandin I and casuarictin) for multi-functional anti-aging performance. Tellirictin® addresses the many signs of aging by delivering brightening, anti-wrinkle, and moisturizing activities, while also protecting the skin from oxidative, inflammatory, proteolytic, and environmental stresses. Applications of Tellirictin® include anti-aging, anti-wrinkle, and skin-brightening regimens, soothing and calming products for sensitive skin, and pre- and post-sun care.   Tellirictin® prevents excessive melanin production to combat hyperpigmentation by inhibiting tyrosinase activity as efficiently as beta-arbutin. Tellirictin® protects collagen and other components of the extracellular matrix (ECM, the structural foundation of the skin) from damaging enzymes (MMPs and elastases) associated with environmental stressors such as environmental pollution and UV (sun) exposure. Tellirictin® modulates microRNAs involved in the beneficial regulation of DNA repair, barrier protection, and anti-inflammatory pathways. 

DermalRx® SRC (R10001) is a yeast-derived oligopeptide that promotes skin renewal by stimulating natural exfoliation via gentle and selective desquamation. Clinical testing demonstrates that DermalRx® SRC enhances exfoliation to reduce skin roughness and improve the appearance of wrinkles in four weeks. DermalRx® SRC gently loosens coarse keratinized cells at the surface, delivering results for applications in anti-aging, anti-wrinkle, anti-blemish, skin brightening, and exfoliation products. DermalRx® SRC is clinically demonstrated to restore skin texture and radiance with documented improvements in the appearance of hyperpigmentation, wrinkles, and other signs of aging. DermalRx® SRC is a selective exfoliant for safe, effective skin renewal.

DermalRx® Acetygen® (R10117) is a botanical active ingredient featuring Agrimonia eupatoria and Ampelopsis grossedentata extract with potent phytochemicals (including dihydromyricetin, myricetin, and other bioactive flavonoids). DermalRx® Acetygen® is a potent senolytic and broad-spectrum epigenetic modulator for applications in skin health and wellness, such as anti-aging products targeting oxidative, environmental, and inflammatory damage. DermalRx® Acetygen® enhances natural skin repair mechanisms to help eliminate dysfunctional senescent cells that contribute to signs of tissue aging. By regulating the histone deacetylase (HAT/HDAC) “switch”, DermalRx® Acetygen® epigenetically restores gene expression to levels found in younger skin for a renewed extracellular matrix (ECM). DermalRx® Acetygen® protects the skin from oxidative stress and inflammatory damage while rejuvenating the tissue for a youthful, healthy appearance. 

Pleiotanicals® Ellagicin®(R10068) is a botanically derived active ingredient containing proprietary acai and pomegranate “superfruit” extracts for antioxidant and anti-aging benefits. Ellagicin® is rich in ellagic acid, anthocyanins, and other natural antioxidants that provide protection from oxidative and proteolytic stress. Ellagicin® protects collagen and other components of the extracellular matrix (ECM, the structural foundation of the skin) from damaging enzymes associated with environmental stressors such as environmental pollution and UV (sun) exposure. Applications of Ellagicin® include anti-aging and anti-wrinkle regimens, soothing and calming products for sensitive skin, and pre- and post-sun care.

DermalRx® FSE (R10111) is a marine bioferment produced from Sargassum vulgare for DNA protection and repair in sun-exposed skin. Rich in bioactive phlorotannins, DermalRx® FSE stimulates the skin’s natural DNA repair process through nucleotide excision repair (NER). Ex vivo studies demonstrate DermalRx® FSE’s DNA protective and reparative effects after UV exposure. DermalRx® FSE also provides strong anti-pollution activity, protecting the skin from damaging oxidation and inflammation. DermalRx® FSE is ideal for anti-aging, de-stressing, soothing and calming, and pre- and post-sun care products.

DermalRx® CKW (R10091) is a plant-derived combinatorial curcuminoid extract that potently and dose-dependently modulates excess sebum production by inhibiting type I and type II 5α-reductase. Clinical evaluation showed significant reductions in sebum production and a visible decrease in facial sheen. DermalRx® CKW is ideal for sebum-regulating products for skin and hair applications, as well as anti-blemish and pore-minimizing formulations.

HEDI® Avocado (R10089) is a unique combination of avocado butter with plant-derived squalane, radish seed extract, and vitamin E in a silicone-free microdispersion carrying more than 30% hydrophobe. Avocado Butter is an occlusive moisturizer to lock in moisture, rich in essential fatty acids and antioxidants. Squalane and radish seed extract act as emollients to help to soothe and soften, and improve skin barrier function. Vitamin E shields from oxidation and free radicals. Applications for HEDI® Avocado include moisturizing treatments for very dry, rough, and cracked skin, skincare products for sensitive skin, and skin, scalp, and hair care conditioning formulas.HEDI® products are stable ingredient blends of aqueous and oil-based materials made using a unique manufacturing process. HEDI® products are ultra-concentrated homogeneous constructs that are infinitely dilutable in aqueous systems. HEDI® products have superior aesthetics while simplifying formulation and manufacturing processes and enhancing the delivery of active ingredients in the formula. HEDI® products can be adjusted to achieve a consistency that is milk-like (pourable and even sprayable), creamy, or paste-like. Tactile properties can be light and silky or velvety and more occlusive. HEDI® products streamline manufacturing processes for time, energy, and cost savings by avoiding additional heating, melting, and mixing steps. HEDI® products are amenable to cold processes and do not require surfactants or emulsifiers.HEDI® products have properties similar to the skin barrier, promoting skin permeability and facilitating delivery through the lipid-rich, waterproof stratum corneum. Finished products have a better feel and provide superior surface coverage when compared to traditionally formulated butters and oils.

Pleiotanicals® Scavenox® HH (R10109) is a highly stable green tea extract with epigallocatechin gallate (EGCG) for long-term antioxidant, anti-inflammatory, and skin-brightening activity. Applications for Scavenox® HH include anti-aging and anti-blemish regimens, skin-brightening and skin tone-balancing systems, and soothing and calming products for sensitive skin. Scavenox® HH protects the skin from oxidative stress with the demonstrated ability to prevent UV-induced lipid peroxidation and scavenging of singlet oxygen. Scavenox® HH also inhibits inflammatory and proteolytic (MMPs and elastase) damage for protection against UV radiation, pollution, and other environmental stressors. These activities offer skin protection and renewal by preserving collagen and other components of the extracellular matrix (ECM, the structural foundation of the skin). Scavenox® HH prevents excessive melanin production to combat hyperpigmentation by inhibiting tyrosinase activity.

Advanced Solutions MariMoist® KPF (R10097) is a sustainable marine biopolymer derived from Chondrus crispus aquatic plants with bio-derived high molecular weight hyaluronic acid (HA), a glycosaminoglycan that is an important natural component of skin. Referred to as the “aloe of the ocean,” MariMoist® KPF is a water-soluble, viscous, hydrocolloid-flowing gel with the highest standards of consistency, quality, and purity.   MariMoist® KPF provides water delivery and a unique textural sensation, improving the aesthetic and tactile properties of finished products while helping to build “body” and impart a rich, luxurious feel. MariMoist® KPF has been demonstrated to bind and deliver water for optimal hydration of the skin, scalp, and hair. Acting as a humectant, MariMoist® KPF is an emollient liquid that instantly moisturizes and softens dry skin.   Applications for MariMoist® KPF include an emollient and hydrator in skin and hair products and a formulation aid or aesthetic modifier of product viscosity and body. MariMoist® KPF is an excellent base for formulations.

Cogesome® SA (R10126) is a novel and proprietary liposome formulation that encapsulates salicylic acid (SA) for improved long-term stability and pH to near physiological levels, optimal miscibility in aqueous and glycolic systems, and superior penetration into the skin. Cogesome® SA is well suited for formulas to address blemished skin, including spot treatments, cleansing, and clarifying products, and overnight resurfacing treatments, as well as other skin and hair formulas.Cogesome® SA supports superior skin penetration properties without the irritation associated with traditional salicylic acid. Cogesome® SA is stable and soluble in water for easy formulation in aqueous-based formulation systems. Cogesome® SA is a completely liposome-encapsulated salicylic acid with high miscibility and a pH of 6-7.4, close to physiological pH. As such, the incorporation of salicylic acid by Cogesome® SA does not significantly impact the pH of the final formulation. Cogesome® SA is a high-technology solution for blemish-prone skin.

DermalRx® HydroSeal (R10067) is a yeast-derived oligopeptide that fortifies the skin barrier functions to restore moisture retention. Clinical testing demonstrates that DermalRx® HydroSeal has impressive moisturizing and anti-wrinkle effects in four weeks. Ideal for applications in anti-aging, anti-wrinkle, moisturization, and skin repair products, DermalRx® HydroSeal rebuilds cell-to-cell junctions for a more compact and less permeable stratum corneum, reducing transepidermal water loss (TEWL) and improving skin hydration. DermalRx® HydroSeal is produced using biofermentation with a proprietary Saccharomyces cerevisiae strain to improve the integrity of the skin barrier for skin moisturization and protection from excessive water loss.

DermalRx® KBGA (R10017) is a proprietary blue-green algal extract with a unique combination of naturally-occurring repair active components for skin and hair moisturization and nourishment. Derived from Aphanizomenon flos-aquae (AFA), DermalRx® KBGA is rich in essential amino acids and fatty acids, proteins, antioxidants, and a full spectrum of minerals.Backed with comprehensive efficacy assays, DermalRx® KBGA increases the skin’s ability to maintain moisture at the skin barrier while protecting collagen and other extracellular matrix components (ECM, the structural foundation of the skin) from oxidative and proteolytic stress. With optimized bioactivity and bioavailability, DermalRx® KBGA addresses dry and damaged skin with applications in anti-aging and anti-wrinkle products, and nourishing, moisturizing skin and hair formulations. 

Advanced Solutions MariMoist® (R10041) is a sustainable marine biopolymer derived from Chondrus crispus aquatic plants with bio-derived high molecular weight hyaluronic acid (HA), a glycosaminoglycan that is an important natural component of skin. Referred to as the “aloe of the ocean,” MariMoist® is a water-soluble, viscous, hydrocolloid-flowing gel with the highest standards of consistency, quality, and purity.   MariMoist® provides water delivery and a unique textural sensation, improving the aesthetic and tactile properties of finished products while helping to build “body” and impart a rich, luxurious feel. MariMoist® has been demonstrated to bind and deliver water for optimal hydration of the skin, scalp, and hair. Acting as a humectant, MariMoist® is an emollient liquid that instantly moisturizes and softens dry skin.   Applications for MariMoist® include an emollient and hydrator in skin and hair products and a formulation aid or aesthetic modifier of product viscosity and body. MariMoist® is an excellent base for formulations.

Pleiotanicals® Holy Basil OSP (R10110) is a proprietary extract of Ocimum sanctum (a plant used in Ayurvedic medicine) for pollution protection and aging prevention in the skin. Holy Basil OSP contains key active molecules, including polyphenols and pentacyclic triterpenoids, that protect against environmental pollution with anti-aging benefits. Holy Basil OSP is ideal for anti-aging, anti-wrinkle, de-stressing, and pollution/UV protection regimens, as well as soothing, calming products for sensitive skin.   Holy Basil OSP reduces a suite of inflammatory mediators in the skin typically induced by exposure to airborne particular matter (PM2.5). Holy Basil OSP protects the extracellular matrix (ECM, the structural foundation of the skin) against damaging oxidative, proteolytic, and inflammatory stress while also modulating collagen and other genes fundamental for ECM structure and integrity.

Pleiotanicals® Volpura® EP (R10098) is an Echinacea purpurea extract to address the signs of aging by supporting the skin’s natural plumping processes. Volpura® EP activates adipogenesis (fat production) within the skin to combat the appearance of wrinkles and sagging from deep within the tissue. Volpura® EP restores fuller, youthful-looking skin by activating an adipogenic modulator that increases the number and size of fat-producing cells. Clinical studies demonstrate that Volpura® EP improves skin mechanical properties with volumizing, anti-wrinkle activity reported after use on the face and hands for 12 weeks. Volpura® EP is recommended for anti-wrinkle, anti-aging, firming, plumping, topical contouring, and volumizing products, as well as regimens to address age-related lipoatrophic disorders.

Cogesome® RL (R10115) is a novel and proprietary pro-liposome formulation that encapsulates retinol (vitamin A) for superior penetration into the skin, improved stability, and optimal miscibility in aqueous systems. The power of retinol is undisputed, accelerating epidermal renewal and enhancing collagen and hyaluronic acid production to reduce the appearance of fine lines, wrinkles, and other signs of aging and improve the skin’s overall appearance. Properly managed retinol is one of the skin’s best supporters, contributing to a healthy glow and youthful appearance.Ex vivo data demonstrate how Cogesome® RL rapidly penetrates the skin, enhancing the penetration and delivery of retinol from the skin’s surface deep into the skin to maximize efficacy. Cogesome® RL significantly reduces biofilm-forming skin resident Cutibacterium acnes, a microbial culprit of blemish flare-ups and skin inflammation. Cogesome® RL is well suited for applications in anti-aging, anti-wrinkle, and anti-blemish formulas, skin exfoliating and resurfacing products, and regimens targeting sun damage and hyperpigmentation.

Grandiciin® (R10124) is an Epimedium extract featuring a beneficial mix of prenylated flavonoids for addressing blemished skin. Applications for Grandiciin® include microbiome-balancing products, anti-blemish and spot treatments, anti-sebum and oil-reducing hair and skin care, and soothing and calming body care regimens for damaged skin. Grandiciin® improves skin health and wellness through microbiome-rebalancing activity, reducing the problematic Cutibacterium acnes (formerly Propionibacterium acnes) biofilms that contribute to inflammation, redness, and blemish formation. Grandiciin® is clinically shown to diminish C. acnes burden on the skin while also reducing sebum (oil) production and signs of inflammation and redness and improving the appearance of blemishes in four weeks. Grandiciin® addresses inflammatory, proteolytic, and oxidative stress to provide an extra layer of protection against tissue damage and scarring in severely blemished skin.

Pleiotanicals® Scavenox® GTE (R10025) is a highly stable green tea extract with epigallocatechin gallate (EGCG) for long-term antioxidant, anti-inflammatory, and skin-brightening activity. Applications for Scavenox® GTE include anti-aging and anti-blemish regimens, skin-brightening and skin tone-balancing systems, and soothing and calming products for sensitive skin.   Scavenox® GTE protects the skin from oxidative stress with the demonstrated ability to prevent UV-induced lipid peroxidation and scavenging of singlet oxygen. Scavenox® GTE also inhibits inflammatory and proteolytic (MMPs and elastase) damage for protection against UV radiation, pollution, and other environmental stressors. These activities offer skin protection and renewal by preserving collagen and other components of the extracellular matrix (ECM, the structural foundation of the skin). Scavenox® GTE prevents excessive melanin production to combat hyperpigmentation by inhibiting tyrosinase activity.

HEDI® Shea Butter E/DU (R10028) is a unique water-based microdispersion of shea butter with dimethicone, urea, and vitamin E. Dimethicone is a skin protectant when formulated at levels of 5% or greater, while urea provides humectancy and helps to condition the skin. Vitamin E shields the skin from oxidation and free radicals.The triglycerides (fat) in shea butter are derived mainly from stearic acid and oleic acid. HEDI® Shea Butter E/DU is an excellent emollient, conditioner, and moisturizer that revitalizes dull, dry skin and promotes skin renewal. Applications for HEDI® Shea Butter E/DU include moisturizing treatments for very dry, rough, and cracked skin, skincare products for sensitive skin, and skin, scalp, and hair care conditioning formulas. HEDI® Shea Butter E/DU can be used in many care products, such as moisturizing creams and emulsions, sunscreens, lip gloss, makeup primers, facial masks, sunless tanning products, hair conditioners, and soaps.USP dimethicone enables OTC Skin Protectant claims when formulating with HEDI® Shea Butter E/DU at concentrations ≥ 5%.HEDI® products are stable ingredient blends of aqueous and oil-based materials made using a unique manufacturing process. HEDI® products are ultra-concentrated homogeneous constructs that are infinitely dilutable in aqueous systems. HEDI® products have superior aesthetics while simplifying formulation and manufacturing processes and enhancing the delivery of active ingredients in the formula. HEDI® products can be adjusted to achieve a consistency that is milk-like (pourable and even sprayable), creamy, or paste-like. Tactile properties can be light and silky or velvety and more occlusive. HEDI® products streamline manufacturing processes for time, energy, and cost savings by avoiding additional heating, melting, and mixing steps. HEDI® products are amenable to cold processes and do not require surfactants or emulsifiers.HEDI® products have properties similar to the skin barrier, promoting skin permeability and facilitating delivery through the lipid-rich, waterproof stratum corneum. Finished products have a better feel and provide superior surface coverage when compared to traditionally formulated butters and oils.

Pleiotanicals® Holy Basil OSE (R10104) is a proprietary extract of Ocimum sanctum (a plant used in Ayurvedic medicine) for pollution protection and aging prevention in the skin. Holy Basil OSE contains key active molecules, including polyphenols and pentacyclic triterpenoids, that protect against environmental pollution with anti-aging benefits. Holy Basil OSE is ideal for anti-aging, anti-wrinkle, de-stressing, and pollution/UV protection regimens, as well as soothing, calming products for sensitive skin.   Holy Basil OSE reduces a suite of inflammatory mediators in the skin typically induced by exposure to airborne particular matter (PM2.5). Holy Basil OSE protects the extracellular matrix (ECM, the structural foundation of the skin) against damaging oxidative, proteolytic, and inflammatory stress while also modulating collagen and other genes fundamental for ECM structure and integrity.

HEDI® Shea Butter SF (R10105) is a unique water-based microdispersion of shea butter with organic-certified babassu oil, plant-derived squalane, sunflower-derived phospholipids, and vitamin E. The triglycerides (fat) in shea butter are derived mainly from stearic acid and oleic acid. Organic certified babassu oil is extracted from wild-picked fruits of the babassu palm tree, offering softening properties with glycerides of lauric, myristic, and oleic acids. HEDI® Shea Butter SF is an excellent emollient, conditioner, and moisturizer that revitalizes dull, dry skin and promotes skin renewal. Applications for HEDI® Shea Butter SF include moisturizing treatments for very dry, rough, and cracked skin, skincare products for sensitive skin, and skin, scalp, and hair care conditioning formulas. HEDI® Shea Butter SF can be used in many care products, such as moisturizing creams and emulsions, sunscreens, lip gloss, makeup primers, facial masks, sunless tanning products, hair conditioners, and soaps.HEDI® products are stable ingredient blends of aqueous and oil-based materials made using a unique manufacturing process. HEDI® products are ultra-concentrated homogeneous constructs that are infinitely dilutable in aqueous systems. HEDI® products have superior aesthetics while simplifying formulation and manufacturing processes and enhancing the delivery of active ingredients in the formula. HEDI® products can be adjusted to achieve a consistency that is milk-like (pourable and even sprayable), creamy, or paste-like. Tactile properties can be light and silky or velvety and more occlusive. HEDI® products streamline manufacturing processes for time, energy, and cost savings by avoiding additional heating, melting, and mixing steps. HEDI® products are amenable to cold processes and do not require surfactants or emulsifiers.HEDI® products have properties similar to the skin barrier, promoting skin permeability and facilitating delivery through the lipid-rich, waterproof stratum corneum. Finished products have a better feel and provide superior surface coverage when compared to traditionally formulated butters and oils.

DermalRx® LuShield™ (R10056) is a proprietary extract of the fragrant flowering Osmanthus fragrans shrub that delivers anti-aging effects through senolytic, antioxidant, anti-inflammatory, and protective activities. DermalRx® LuShield™ addresses cellular senescence due to environmental and dietary stressors while also protecting collagen and the extracellular matrix (ECM, the structural foundation of the skin) from the damaging effects of advanced glycation end-products (AGEs), UV radiation, free radicals, and pollution (PM2.5). DermalRx® LuShield™ protects the skin to facilitate the natural repair, rebuilding, and restructuring of skin and skin matrices for a healthy and youthful appearance.  

HEDI® Mango Butter (R10076) is a unique water-based dispersion of mango butter with babassu oil, squalane, and vitamin E in a silicone-free microdispersion carrying more than 30% hydrophobe. HEDI® Mango Butter is a plant-derived alternative for paraffin and silicone-based emollients. Applications for HEDI® Mango Butter include moisturizing treatments for very dry, rough, and cracked skin, skincare products for sensitive skin, and skin, scalp, and hair care conditioning formulas. A soft solid with a very slight sweet scent, Mango Butter exhibits excellent moisturizing properties and good lubricity. Mango Butter, obtained from de-shelled fruit kernels of the mango tree, has natural antioxidant, anti-inflammatory, and antimicrobial properties. Organic certified babassu oil is extracted from wild-picked fruits of the babassu palm tree, offering softening properties with glycerides of lauric, myristic, and oleic acids. HEDI® products are stable ingredient blends of aqueous and oil-based materials made using a unique manufacturing process. HEDI® products are ultra-concentrated homogeneous constructs that are infinitely dilutable in aqueous systems. HEDI® products have superior aesthetics while simplifying formulation and manufacturing processes and enhancing the delivery of active ingredients in the formula. HEDI® products can be adjusted to achieve a consistency that is milk-like (pourable and even sprayable), creamy, or paste-like. Tactile properties can be light and silky or velvety and more occlusive. HEDI® products streamline manufacturing processes for time, energy, and cost savings by avoiding additional heating, melting, and mixing steps. HEDI® products are amenable to cold processes and do not require surfactants or emulsifiers.HEDI® products have properties similar to the skin barrier, promoting skin permeability and facilitating delivery through the lipid-rich, waterproof stratum corneum. Finished products have a better feel and provide superior surface coverage when compared to traditionally formulated butters and oils.

HEDI® Hemp Seed Oil (R10116) is an elegant water-based microdispersion carrying more than 30% hemp seed oil that is rich in proteins, lecithin, vitamins, minerals, and essential fatty acids: linoleic acid (omega-6) and alpha-linolenic acid (omega-3). Applications for HEDI® Hemp Seed Oil include skin, scalp, and hair softening and moisturizing regimens, as well as skin barrier repair and microbiome-modulating products. Hemp seed oil is an excellent emollient that promotes a youthful appearance by reducing fine lines and wrinkles, plumping the skin, and increasing skin elasticity. HEDI® Hemp Seed Oil is a natural, plant-derived silicone alternative.HEDI® products are stable ingredient blends of aqueous and oil-based materials made using a unique manufacturing process. HEDI® products are ultra-concentrated homogeneous constructs that are infinitely dilutable in aqueous systems. HEDI® products have superior aesthetics while simplifying formulation and manufacturing processes and enhancing the delivery of active ingredients in the formula. HEDI® products can be adjusted to achieve a consistency that is milk-like (pourable and even sprayable), creamy, or paste-like. Tactile properties can be light and silky or velvety and more occlusive. HEDI® products streamline manufacturing processes for time, energy, and cost savings by avoiding additional heating, melting, and mixing steps. HEDI® products are amenable to cold processes and do not require surfactants or emulsifiers.HEDI® products have properties similar to the skin barrier, promoting skin permeability and facilitating delivery through the lipid-rich, waterproof stratum corneum. Finished products have a better feel and provide superior surface coverage when compared to traditionally formulated butters and oils.

Pleiotanicals® Volpura® EPO (R10125) is a plant-derived active ingredient extracted from Echinacea purpurea, known for its abundance in various active compounds, notably fatty acid alkylamides. This ingredient demonstrates the ability to activate PPAR-γ, which serves as the master regulator of adipogenesis. Its benefits lie in enhancing fat production by stimulating the differentiation of pre-adipocytes into adipocytes. This property makes it suitable for incorporation into formulations targeting anti-wrinkle effects, particularly for addressing expression lines in the forehead and nasolabial fold areas. Additionally, it finds application in facial contouring, re-firming, and plumping regimens aimed at addressing age-related lipoatrophy.