Pleiotanicals® Tellirictin® (R10047)

Tellirictin® (R10047) is a proprietary clove flower extract containing natural gallate-based pleiotropic compounds (tellimagrandin I and casuarictin) for multi-functional anti-aging performance. Tellirictin® addresses the many signs of aging by delivering brightening, anti-wrinkle, and moisturizing activities, while also protecting the skin from oxidative, inflammatory, proteolytic, and environmental stresses. Applications of Tellirictin® include anti-aging, anti-wrinkle, and skin-brightening regimens, soothing and calming products for sensitive skin, and pre- and post-sun care.   Tellirictin® prevents excessive melanin production to combat hyperpigmentation by inhibiting tyrosinase activity as efficiently as beta-arbutin. Tellirictin® protects collagen and other components of the extracellular matrix (ECM, the structural foundation of the skin) from damaging enzymes (MMPs and elastases) associated with environmental stressors such as environmental pollution and UV (sun) exposure. Tellirictin® modulates microRNAs involved in the beneficial regulation of DNA repair, barrier protection, and anti-inflammatory pathways. 

Brand: Pleiotanicals (9 products)

INCI Name: Eugenia Caryophyllus (Clove) Flower Extract

Ingredient Origin: Natural Origin, Plant Origin

Functions: Anti-Aging Agent

Labeling Claims: Gluten-free, Natural, Naturally Derived, Non-Irritant, Not Tested on Animals, Plant-Based, Sustainable, Vegan

Benefit Claims: Anti-Aging, Anti-Inflammatory, Anti-Pollution, Antioxidant Properties, Brightening, Calming, Compatibility, DNA Protection, Irritation Reduction, Oxidation Protection, Rejuvenating, Skin Protection, Soothing, Stress Reducing, Suitable for Sensitive Skin, UV Protection

Certifications & Compliance: California Proposition 65

Enhanced TDS

Knowde-enriched technical product data sheet

Identification & Functionality

Carrier
INCI Name
Ingredient Origin
Cosmetic Ingredients Functions
Technologies
Product Families
Origin
Tellirictin®, a proprietary extraction of clove flowers that functions across many levels to protect and rejuvenate skin.

Features & Benefits

Benefit Claims
Labeling Claims
Benefits & Claims
  • A botanically derived active produced from clove flower via Biocogent’s proprietary extraction process
  • Contains high concentrations of active tellimagrandin I and polyphenols
  • Modulates 13 microRNAs for beneficial regulation of DNA repair, matrix protection, and anti-inflammatory pathways
  • Protects the extracellular matrix via inhibition of proteolytic stress (elastase and MMPs)
  • Inhibits tyrosinase activity as efficiently as beta-arbutin
  • Provides strong antioxidant activity against environmental stress

Applications & Uses

Markets
Applications
Application Format
Skin Care Applications
Sun Care Applications
Use Level
0.5 - 3%
Applications
  • Anti-aging regimens protective against oxidative and proteolytic stress (UV exposure, pollution, etc.)
  • Soothing and calming for sensitive skin
  • Pre- and post-sun skin care
  • Skin brightening and skin tone balancing systems
  • Post-shave lotions and gels to relieve irritation
Compatibility and Formulation

Tellirictin® is compatible with most conventional ingredients used in skincare products. Add in the last step of formulation when temperature is below 50°C. Mix well before use.

Properties

Physical Form

Regulatory & Compliance

Certifications & Compliance
Regulatory Information
  • This product has not been tested on animals, and our company adheres to the written provisions of such animal rights organizations as Leaping Bunny and Cruelty/Free International.
  • This product contains no animal products. It is manufactured using only plant based or synthetically derived (non-animal origin) materials and is thereby declared a Vegan Product.
  • All materials used to produce this product are procured using sustainable sourcing practices.
  • This product is manufactured in accordance with the current Good Manufacturing Practices (cGMP) requirements established by the U.S. Food and Drug Administration (FDA) for cosmetics. Furthermore, Biocogent, LLC, and this production facility(ies), are registered as cosmetic manufactures with the FDA.
  • REACH compliance: All of the ingredients (substances) used in the manufacture of this product (mixture)are either registered under REACH, or qualify for an Article 2 (low volume of less than 1 metric ton), Annex IV or Annex V exemption, making our product REACH compliant.
  • Proposition 65 compliance: Based upon Biocogent LLC’s knowledge of our business operations and chemical formulations, no chemicals listed by the State of California Environmental Protection Agency are used in our products, or as a processing aid for any product manufactured in our facility.

Technical Details & Test Data

Test Data

Tellirictin® Inhibition of Matrix Degrading Enzymes

Tellirictin® protects the matrix by inhibiting the enzymes that degrade it, including MMP-1, MMP-8, and HLE in skin.

 

Tellirictin® Inhibition of Tyrosinase

 

Tellirictin® delivers skin brightening effects by inhibiting tyrosinase, the enzyme responsible for producing melanin pigment in skin.

Safety & Health

Safety
Human Repeat Insult Patch Testing (HRIPT) under semi-occlusive conditions indicated that Tellirictin® did not perform as a primary skin irritant or as a primary skin sensitizer when tested neat. Ocular irritation testing predicted that Tellirictin® would be a Minimal/Mild ocular irritant at recommended use levels.

Storage & Handling

Shelf Life
12 Months
Storage Condition
Tellirictin® should be stored at room temperature in original packaging away from heat and light.