Products in Pharmaceuticals & Nutraceuticals: Pellets

Shin-Etsu AQOAT® AS-MF -Hypromellose acetate succinate (HPMCAS, NF, JP) is an enteric coating material that can be used in aqueous or organic media.It is also used as solubility enhancement of poorly soluble APIs.

L-HPC (low-substituted hydroxypropyl cellulose NF, JP, EP) This dual functioning excipient acts as both a disintegrant and binder. It is not the same as HPC. L-HPC is insoluble in water. It is an effective disintegrant due to its swelling action in water. Because is has good compressibility, it functions as a dry binder.L-HPC benefits are:Enhanced stability because it is non-ionic and has low water activityIt is peroxide free and provides excellent compatibility for oxygen sensitive APIsImproved disintegrationA variety of grades are available depending on the application.L-HPC LH-11 is suitable for direct compression and prevents capping during compression.

L-HPC (low-substituted hydroxypropyl cellulose NF, JP, EP) This dual functioning excipient acts as both a disintegrant and binder. It is not the same as HPC. L-HPC is insoluble in water. It is an effective disintegrant due to its swelling action in water. Because is has good compressibility, it functions as a dry binder.L-HPC benefits are:Enhanced stability because it is non-ionic and has low water activityIt is peroxide free and provides excellent compatibility for oxygen sensitive APIsImproved disintegrationA variety of grades are available depending on the application.L-HPC LH-22 is suitable for direct compression.

Amorphous solid dispersion is a technology for solubility enhancement of drugs.Shin-Etsu AQOAT® AS-LMP is used as solubility enhancement of poorly soluble APIs.

HPMCP is a monophthalic acid ester of hypromellose.HP-50 is enteric coating agent soluble at lower pH

L-HPC (low-substituted hydroxypropyl cellulose NF, JP, EP) This dual functioning excipient acts as both a disintegrant and binder. It is not the same as HPC. L-HPC is insoluble in water. It is an effective disintegrant due to its swelling action in water. Because is has good compressibility, it functions as a dry binder.NBD Grades:Better flowability because of the non-fibrous particle shapeBetter compressibilityBetter tasteEnhanced stability because it is non-ionic and has low water activityIt is peroxide free and provides excellent compatibility for oxygen sensitive APIsA variety of grades are available depending on the application.L-HPC NBD-020 is suitable for wet granulation.

Shin-Etsu AQOAT® AS-LF -Hypromellose acetate succinate (HPMCAS, NF, JP) is an enteric coating material that can be used in aqueous or organic media.It is also used as solubility enhancement of poorly soluble APIs.

Shin-Etsu AQOAT® AS-HG-Hypromellose acetate succinate (HPMCAS, NF, JP) is an enteric coating material that can be used in aqueous or organic media.It is also used as solubility enhancement of poorly soluble APIs.

L-HPC (low-substituted hydroxypropyl cellulose NF, JP, EP) This dual functioning excipient acts as both a disintegrant and binder. It is not the same as HPC. L-HPC is insoluble in water. It is an effective disintegrant due to its swelling action in water. Because is has good compressibility, it functions as a dry binder.L-HPC benefits are:Enhanced stability because it is non-ionic and has low water activityIt is peroxide free and provides excellent compatibility for oxygen sensitive APIsImproved disintegrationA variety of grades are available depending on the application. L-HPC LH-31 is suitable for wet granulation, pellet extrusion and layering.

Shin-Etsu AQOAT® AS-LG -Hypromellose acetate succinate (HPMCAS, NF, JP) is an enteric coating material that can be used in aqueous or organic media.It is also used as solubility enhancement of poorly soluble APIs.

Amorphous solid dispersion is a technology for solubility enhancement of drugs. Shin-Etsu AQOAT® AS-HMP is used as solubility enhancement of poorly soluble APIs.

Shin-Etsu AQOAT® AS-MG -Hypromellose acetate succinate (HPMCAS, NF, JP) is an enteric coating material that can be used in aqueous or organic media.It is also used as solubility enhancement of poorly soluble APIs.

HPMCP is a monophthalic acid ester of hypromellose.HP-55 is a regular grade enteric coating agent.

AquaPolish® STA has been developed for the fast coating of oral solid dosage forms. It is easily soluble and a reproducible high-quality film coating can be guaranteed. Due to its high solid content of 20–25% in the dispersion, a fast application at low process temperatures will improve your production process and save time. Additionally, your product gains a small barrier against moisture.

AquaPolish G has been developed for the coating of all kinds of solid dosage forms. It is easily soluble and a reproducible high-quality film coating can be guaranteed. The widely approved, mineral colors of Candurin® are based on natural silicate combined with titanium dioxide and/or iron oxide.

AquaPolish® SR creates a strong and insoluble film coating with good adhesion, through which the active ingredient diffuses. The use of highquality, insoluble cellulose ethers or Ammonio Methacrylate Copolymer (Type A, Type B) in combination with soluble cellulose ethers, plasticizing and coloring additives, guarantees film coatings that are always reproducible. By varying the type and amount of the cellulose ethers used, a wide range of release profiles can be achieved.

BIOGRUND’s one-step film coating system AquaPolish® OM perfectly masks bad and strong smelling actives (e. g. herbal extracts). Sealing these characteristics by using AquaPolish® OM enables a pleasant application for the consumer and increases patient compliance. It provides a protective and economical coating on tablets, pellets, granules and capsules without influencing the disintegration time.

AquaPolish® TC is a combination of HPMC, HPC and other cellulose ethers with taste masking additives. Due to the further additives, which form a hardly soluble film, a tastemasking is achieved.

AquaPolish® PRO is a dry milled powdered compound is a ready-to-use film coating system that provides moisture sealing properties and a highly flexible film on solid oral dosage forms for immediate release profiles.

BIOGRUND provides a wide range of ready-to-use film coating products which includes AquaPolish® MS. It's a moisture sealing product. It provides a protective and fast soluble film on tablets, pellets, granules and capsules. It is a combination of selected film-forming cellulose ethers with plasticizing and coloring additives. The use of hydrophobic excipients gives excellent protection against moisture. The product is designed to improve the coating process and can be applied using conventional or modern coating equipment. It is a homogeneous, dry-milled, powdered compound, developed for the coating of all kinds of solid dosage forms. It is easily soluble and a reproducible high-quality film coating can be achieved. Clear, white and colored preparations can be tailor-made according to customer requirements. Contact us for more information.

AquaPolish® HS is a combination of film-forming polymer METHOCEL™ Premium VLV with plasticizing and coloring additives. The very low viscosity of HPMC enables high solid content dispersions for high speed productivity.

BIOGRUND’s one-step film coating system AquaPolish® E provides a protective film with excellent enteric properties. And with its superior light, oxygen and moisture protection, it is recommended for tablets, pellets, capsules and granules.

AquaPolish® C has been developed to improve running production processes. Furthermore, it is an ideal basis for researching new solutions. The contract manufactured compound is a unique, dry milled, homogeneous blend of film coating polymers, plasticizing and coloring additives and other excipients. It can be applied by using conventional or modern coating equipment.

BIOGRUND’s one-step film coating system AquaPolish® PVA provides a protective and fast soluble film on tablets, pellets, granules and capsules. It is a unique, dry milled, homogeneous blend of selected filmforming polymers with coloring and a few plasticizing additives. AquaPolish® PVA is a combination of polyvinyl alcohol and optional HPC, which gives excellent moisture sealing by using aqueous solvent applications.

BIOGRUND’s one-step film coating system AquaPolish® provides a protective and fast release film on tablets, pellets, granules and capsules. It is a unique, dry milled, homogeneous blend of selected film-forming cellulose ethers with plasticizing and coloring additives.

CELLETS® 780 is smallest size starter core(<200 μm) for the production of micropellets and MUPS tablet formulation incl.ODT.

CELLETS® 127 is an insoluble starter pellets for combination drug formulations

CELLETS® 175 is an insoluble starter pellets for combination drug formulations

CELLETS® 350 has shorter and more stable layering process with high yields due to low friability and non-solubility in comparison to standard starter cores.

CELLETS® 200 is highly spherical and narrow particle size for reproducible production process and content uniformity.

CELLETS® 700 is smallest size starter core(<200 μm) for the production of micropellets and MUPS tablet formulation incl.ODT.

CELLETS® 500 has shorter and more stable layering process with high yields due to low friability and non-solubility in comparison to standard starter cores.

CELLETS® 1000 is smallest size starter core(<200 μm) for the production of micropellets and MUPS tablet formulation incl.ODT.

CELLETS® 100 is produced of microcrystalline cellulose and purified water for less interaction with the API.

CELLETS® 263 is highly spherical and narrow particle size for reproducible production process and content uniformity.