Products in Excipients: Sweetener

SweetPearl® P90 - MALTITOL powder is used as a filler and filler/binder. SweetPearl® provides stability to your formulation due to its chemical stability and low hygroscopicity. The SweetPearl® range offers you a choice between various particle sizes and densities to meet your formulation needs. It can be used in pharmaceutical applications such as swallowable tablets, chewable tablets, effervescent tablets, coatings, and medicated confectionery. As a patient-friendly excipient, it allows you to formulate non-cariogenic, non-acidogenic, and sugar-free formulations to address the widest patient population.

NEOSORB® BioPharma Low endotoxin grade sorbitol provides protein stabilization in your biopharmaceutical downstream applications. Known for its high water solubility, it is a proven formulation aid for biopharmaceuticals. Sorbitol is used as an excipient in over 35 commercial mAbs, therapeutic proteins and vaccines. Roquette's in process quality controls ensure a consistent supply of raw materials and excipients to help bring your biologics to life. Through our integrated supply chain and rigorous quality systems, we reduce the risks associated in biopharmaceutical manufacturing. NEOSORB® BioPharma is suitable for use in biopharmaceutical manufacturing and as an excipient for injectable dosage forms. Contact us today to talk about our multi-compendial materials - EP, JP, and USP.

PEARLITOL® Mannitol pharma range is used in pharmaceutical and nutraceutical applications as a filler, filler/binder and bulk sweetener for various oral dosage forms. Applications Swallowable, orally dispersible, chewable and effervescent tablets, Lozenges Blends Granules Pellets premix Medicated confectionery Benefit Suitable for use in formulations addressing all types of patient populations, including pediatric and diabetic Features Directly compressible Unique blend of exceptional physical and chemical stability No hygroscopicity Organoleptic, non-cariogenic and sugar-free properties

LYCASIN® Maltitol liquids are used as vehicle and humectant for syrups, suspensions and as sweetener in lozenges and medicated confectionary. LYCASIN® has taste and sweetness properties ideal for the preparation of sugar-free syrups made for pediatric and diabetic population.

SWEETPEARL® P35 is a product with the chemical name maltitol, serving as a sweetener, nutritive sweetener, and sugar substitute. It falls under food ingredient functions, specifically as a nutritive sweetener and sugar substitute. The labelling claims for this product include being biodegradable. SWEETPEARL® P35 is primarily targeted at the food and nutrition markets and is commonly used in chewing gum applications. It is water-soluble and presents as a white crystalline powder with no discernible odor, offering a cool and sweet taste.

NEOSORB®70/70 B Sorbitol liquid crystallizing and non-crystallizing products are widely used excipients as vehicle in liquid dosage forms and as a humectant in semi solids. They can be used in various pharmaceutical and nutraceutical applications including lozenges, medicated confectionary, syrups, suspensions, creams and pastes. These NEOSORB® 70/70 B brand materials are part of a large family of Roquette polyol compounds containing sorbitol and other hydrogenated long chain oligomers and polymers. NEOSORB®70/70 B solutions can be used as substitutes for sucrose and meet organoleptic (natural sweetness) and health requirements (i.e they are sugar-free, low-calorie, do not induce dental caries, and may be advised for diabetics). These grades will differ by a difference of composition and concentration in sorbitol and other polyols.

XYLISORB® Xylitol powders can be used in pharmaceutical and nutraceutical applications as a filler, filler/binder and bulk sweetener that provides nutrient benefits. Applications Swallowable tablets Medicated confectionaries Features Five-carbon polyol with a characteristic crystalline shape Low calorie sugar-free ingredient with high natural sweetness Suitable for use in formulations addressing pediatric and diabetic patient populations

NEOSORB® XTAB 300S is a directly compressible sorbitol powder that can be used for very hard, sugar-free tablets with high flavor load. Benefits Delivers a smooth, hard and uniform colored surface Provides a clean, cooling effect Does not produce acids or cause dental plaque or tooth decay Nutritional benefits (maintenance of tooth mineralization, tooth-friendly generic EU claims) recognized by European regulations Features Non-cariogenic Sugar-free

NEOSORB® Sorbitol pharma is used in pharmaceutical and nutraceutical formulations as a filler, filler/binder and bulk sweetener for oral dose applications. It can also be used as a plasticizing agent well-adapted to starches in coating/film forming applications. Applications Powder blends Premixes Granules Pellets Swallowable, chewableand effervescent tablets Medicated confectionary Features Excellent tableting properties Non-cariogenic Non-acidogenic Sugar-free Suitable for use in formulations addressing pediatric and diabetic patient populations

XYLISORB® Xylitol powders are used in coatings for pharmaceutical and nutraceutical formulations, and as a filler, filler/binder and bulk sweetener that provides nutrient benefits. Applications Swallowable tablets Medicated confectionery Features Five-carbon polyol with a characteristic crystalline shape Low-calorie, sugar-free ingredient with high natural sweetness Suitable for use in formulations addressing pediatric and diabetic patient populations

XYLISORB® Xylitol powders can be used as a low calorie, sugar-free ingredient that provides high natural sweetness. A five-carbon polyol with a characteristic crystalline shape, it provides excipient benefits as a coating, filler and filler/binder and nutrient benefits as a bulk sweetener. It can be used: in pharmaceutical and nutraceutical oral dosage applications, including swallowable tablets and medicated confectioneries in formulations addressing all types of patient populations, including pediatric and diabetic

NEOSORB® 70/02 B is a liquid sorbitol with crystalline properties. This versatile solution serves as a potent bulk sweetener for liquid dosage forms and a humectant for semi-solids. Comprising sorbitol and hydrogenated oligomers, NEOSORB® 70/02 B provides an ideal alternative to sucrose, aligning with organoleptic and health needs. It's sugar-free, low-calorie, non-cariogenic, and suitable for diabetics, making it a smart choice for your formulation needs.

PEARLITOL® Mannitol pharma range is used as a filler and filler/binder. The PEARLITOL® range offers a unique blend of exceptional physical and chemical stability with no hygroscopicity. Using different texturizing technologies, we have designed a crystalline range of directly compressible PEARLITOL® with various particle sizes, allowing you to find the right product. With great organoleptic, non-cariogenic, and sugar-free properties. PEARLITOL® is suitable to be used in formulations addressing all types of patient populations, including paediatrics and diabetics.  PEARLITOL® can be used in various oral dosage forms in both pharmaceutical and nutraceutical applications, including swallowable tablets, orally dispersible tablets, chewable tablets, effervescent tablets, lozenges, blends, granules, pellet premixes, and medicated confectionary.

PEARLITOL® 200 GT-EXP is a direct compression excipient specifically formulated to enhance the manufacturing process of tablets. This exceptional excipient is designed to address key challenges such as capping, while improving flowability and tabletability. PEARLITOL® 200 GT-EXP is a granulated form of mannitol known for its outstanding physical and chemical stability. With its high API compatibility and non-hygroscopic nature, it ensures consistent quality and performance in pharmaceutical formulations. As a non-cariogenic and non-acidogenic sugar-free sweetener, it is suitable for various patient populations, including pediatric and diabetic individuals. PEARLITOL® 200 GT-EXP finds application in a wide range of dosage forms, including tablets (lozenges, swallowable, orally dispersible, chewable, and effervescent) as well as powder blends (sachets, oral stick packs, and hard gelatin capsules).

PEARLITOL® 25 C Mannitol is a filler and bulk sweetener that can be used for pharmaceutical oral dosage applications. Benefits BSE-free Halal and Kosher certified Melamine-free Non-carcinogenic Non-hazardous Sugar-free TSE-free Vegan Features High physical and chemical stability Cooling effect Non-cariogenic Low hygroscopicity

Tooth-friendly NEOSORB® XTAB 300S is a directly compressible sorbitol powder for very hard sugar-free tablets with high flavor load. Benefits Delivers a smooth, hard and uniform colored surface. Provides a clean, cooling effect. Does not produce acids or cause dental plaque or tooth decay. Nutritional benefits (maintenance of tooth mineralization, tooth-friendly generic EU claims) recognized by European regulations.

NEOSORB® P30/60 is a sugar-free, low-caloric bulk sweetener that provides various functional properties in confectionery, bakery, and seafood products. It is commonly used as a sugar replacement in sugar-free confectionery and enables manufacturers to meet consumer demand for a wide range of textures in tooth-friendly chewing gums, which contribute to oral health.

Zerose™ Erythritol is a non-nutritive sweetener, sugar substitute, and sweetening agent. It provides the same sweet taste and mouthfeel as sucrose (table sugar), but with zero calories. This makes it an excellent choice for achieving reduced-calorie claims that traditional sugar alternatives cannot match. Notably, Zerose™ Erythritol is not only calorie-free but also highly digestive-tolerant, does not lead to increases in blood glucose or insulin levels, and is non-cariogenic.

Cargill Granulated Sugar Cane is made by crystallizing a purified and filtered syrup extracted from sugar cane. The resulting sugar is white in color and has a sucrose content of not less than 99.85 percent. It is suitable for use in various applications such as pharmaceuticals, jams, jellies, meats, chewing gum, dairy products, condiments, pickles, bakery products, cereals, liquid sugar, powdered sugar, candies, and powdered drink mixes.

Zerose™ Erythritol Standard Granular Pharma Excipient is a high-purity, white crystalline powder of erythritol produced by fermentation of carbohydrates. It is recommended for use in nutraceutical and medicinal candies, lozenges, coatings, confectionery items, medicinal capsules, powders, liquids, toothpaste, topical applications, and ointments. It can be used in various tablet forms and helps improve the sensorial acceptance of oral products by masking the off taste of certain actives.

ADM Dextrose Monohydrate is produced through the enzymatic hydrolysis of starch, followed by purification, concentration, crystallization, and drying. It is a white calibrated powder with a refreshing sweet taste and bland odor, complying with EU and manufacturing country directives and regulations on foods and food ingredients, considered Non GMO. Dextrose, also known as glucose, is a simple sugar derived from various botanical sources like corn, wheat, fruits, and honey. It is widely used in a variety of products, including pharmaceutical applications, owing to its versatile functionality and benefits beyond sweetness.

MALTISWEET® 3145 Maltitol Syrup,NF/FCC - 271051 is a non-crystallizing syrup bulking agent for solution suspension and can act as a humectant, texturing agent, and stabilizing aid. It is non-reactive and non-cariogenic. It typically contains at least 60% maltitol, and it is used as a replacement for sucrose and corn syrup in sugar-free and reduced-sugar applications. Its sweetness and taste are similar to sugar. It meets the requirements of USP/ NF.

CERELOSE® Coarse Dextrose NF - 020350 is a coarse monohydrate dextrose product designed for applications requiring a unique coarser particle size profile, rounded and porous particle shape. This free-flowing material is manufactured according to IPEC cGMPs and tested for compliance with Dextrose Excipient NF standards. It can be used as an effective bulking agent in tablets, capsules, and other solid dosage forms to increase their volume and improve their handling properties besides having good compression ability. It meets the requirements of USP/ NF.

MALTISWEET® 3145 NON-GMO - 27105190 is a non-crystallizing syrup bulking agent for solution suspension and can act as a humectant, texturing agent, and stabilizing aid. It is non-reactive and non-cariogenic. It typically contains at least 60% maltitol and is used as a replacement for sucrose and corn syrup in sugar-free and reduced-sugar applications. Its sweetness and taste are similar to sugar. This product is produced under Ingredion Incorporated’s TrueTrace™ Program for non-GM products. It meets the requirements of USP/ NF.

IMAG Organics Organic 100% Blue Agave Crystallized Syrup is a delicious sweetener manufactured 100% from the Agave tequilana Weber Blue variety (the only raw material). Organic 100% Blue Agave Crystallized Syrup is obtained by the hydrolyzing the inulin stored in the Agave heart producing a highly rich fructose (≥ 98%) syrup with greater sweetness (approx. 1.4 times sweeter than table sugar), low glycemic index* (17.1) and antioxidant capacity.

IMAG Organics Organic 100% Blue Agave Syrup is a delicious sweetener manufactued 100% from the Agave tequilana Weber Blue variety (the only raw material). Organic 100% Blue Agave Syrup is obtained by hydrolyzing the inulin stored in the heart of the Agave, producing a highly rich fructose (≥ 84%) syrup with greater sweetness (approx. 1.5 times sweeter than table sugar), low glycemic index* (17.1) and antioxidant capacity. • (Tested by INQUIS GI).

IMAG Organics Organic Raw 100% Blue Agave Syrup is a delicious sweetener manufactured 100% from the Agave tequilana Weber Blue variety (the only raw material). The Organic Raw 100% Blue Agave Syrup is obtained by the hydrolyzing the inulin stored in the heart of the Agave, producing a highly rich fructose (≥ 84%) syrup with greater sweetness (approx. 1.5 times sweeter than table sugar), low glycemic index* (17.1) and antioxidant capacity. • (Tested by INQUIS GI).

HTBA Neohesperidin dihydrochalcone Pharma Grade serves as an excipient specifically designed to improve the bitter aftertaste of medicines. This product complies with EP and USP standards, ensuring its quality and suitability for pharmaceutical applications. Its primary markets are in the Healthcare and pharmaceutical industries, and it is commonly used in oral formulations and API manufacturing to enhance the taste and overall palatability of medicinal products.

Pharm-Rx Sucralose acts as a sweetener within pharmaceuticals and nutraceutical technologies. Comprising sucralose, it falls under flavors and taste maskers in excipients. Pharm-Rx Sucralose is commonly employed for its sweetening properties in various formulations.

Bordas Flavonoid Neohesperidin DC Pharma Grade acts as a purpose-built excipient meticulously crafted to ameliorate the lingering bitterness in medicinal formulations. Adhering to the highest quality benchmarks set by EP and USP standards, this product guarantees excellence and appropriateness for pharmaceutical applications. It finds its principal applications in the healthcare and pharmaceutical sectors, where it is frequently employed in the development of oral formulations and the manufacturing of Active Pharmaceutical Ingredients (APIs). Its role extends to refining the taste and overall palatability of medicinal products, ensuring a more pleasant and patient-friendly experience.

Pharm-Rx Sorbitol acts as a sweetener within pharmaceuticals and nutraceutical technologies. Comprising sorbitol, it falls under flavors and taste maskers in excipients. Pharm-Rx Sorbitol is commonly employed for its sweetening properties in various formulations.

Pharm-Rx Xylitol DC is a sweetener with applications in the healthcare and pharma industries. It functions as a sweetener, and its manufacturing technology involves direct compression. The product is in powder form and is water-soluble. The labeling claims state that it is not listed in California Proposition 65.

Pharm-Rx Honey is a natural sweetener made from honey, ideal for use in food and pharmaceutical products. Rich in nutrients, it serves as a nutritive sweetener.

Pharm-Rx Mannitol Granular is a solid binder, humectant, moisturizing agent, fragrance, and conditioner. It is made of mannitol granules and can also be used as a sweetener in pharmaceutical and nutraceutical products.

Corn Syrups Du-Sweet 4 - 42% High Fructose is a versatile sweetener that finds applications in various industries. This high fructose corn syrup serves as a nutritive sweetener in food and nutrition, as well as pharmaceutical and animal feed sectors. It imparts sweetness and flavor enhancement to a wide range of products. Du-Sweet 4 - 42% High Fructose Corn Syrup is widely used in confectionery, dairy, desserts, beverages such as carbonated drinks, juice, and convenience foods. It is also suitable for applications in bakery items like cakes, pastries, and jams, as well as in canned fruits and dried fruits. With allergen-free and GMO-free labeling claims, this syrup meets the requirements of consumers. It is certified kosher, SQF Certified, and complies with GRAS and GMP regulations.

Bordas Neohesperidin dihydrochalcone Pharma Grade acts as a purpose-built excipient meticulously crafted to ameliorate the lingering bitterness in medicinal formulations. Adhering to the highest quality benchmarks set by EP and USP standards, this product guarantees excellence and appropriateness for pharmaceutical applications.It finds its principal applications in the healthcare and pharmaceutical sectors, where it is frequently employed in the development of oral formulations and the manufacturing of Active Pharmaceutical Ingredients (APIs). Its role extends to refining the taste and overall palatability of medicinal products, ensuring a more pleasant and patient-friendly experience.