Products in Carriers & Bulking Agents: Solubilizer

Shin-Etsu AQOAT® AS-HF-Hypromellose acetate succinate (HPMCAS, NF, JP) is an enteric coating material that can be used in aqueous or organic media. It is also used as solubility enhancement of poorly soluble APIs.

Captex® 100 is a diester formed from a reaction of selected high-purity vegetable fatty acids and propylene glycol. It is Kosher certified. Captex® 100 is totally miscible in mineral oil and in 95% ethanol. It has a lower viscosity than mineral oil. Captex® 100 is an excellent skin emollient and produces a smooth, non-greasy, powdery after-feel with shine. Due to its excellent solvency, Captex® 100 works exceptionally well as a substitute for mineral oil in cosmetic makeup-remover formulas. Because of its unique properties, viscosity, and miscibility with other cosmetic components, Captex® 100 offers advantages in suncare and haircare products where spreadability and shine are desired. The non-oily character, excellent stability, bland taste, and neutral odor make this product an ideal choice as a solubilizer and carrier of vitamins, colors, and flavors for selected pharmaceutical and nutritional formulations, or processing aids such as pan and mold-release agents. It is manufactured in USA.

Capmul® MCM is a mono- and diglyceride with unique properties and versatility as a solvent, emulsifier, and emollient for creams, lotions, and rinse-off applications. This high purity distilled monoester is effective as a preservative alternative, based on natural materials, and makes an excellent primary or secondary surfactant in personal care products and cosmetics. It is used to produce stable emulsions, to modify viscosity and can act as a carrier and vehicle in selected applications. It is manufactured in USA.

Captex® 170 EP is an ester prepared from the dehydration of coco fatty alcohols with caprylic and capric acids. It is a polar lipid suitable for solubilizing many types of active ingredients. It may also enhance translocation of API. It is manufactured in USA.

CAPTEX® 200 is a full-refined ester manufactured by the esterification of selected vegetable fatty acids (mainly caprylic and capric) with propylene glycol. It is miscible with most organic solvents including 95% ethanol. The low viscosity, excellent lubricity, low irritation, and the relatively non-oily character of CAPTEX® 200 makes it ideally suited for a variety of nutritional, personal care, and cosmetic applications. CAPTEX® 200 carries Kosher certification and has excellent stability. It is manufactured in USA.

Capmul® MCM EP/NF is a mixture of monoacylglycerols, obtained by direct esterification of glycerol with caprylic (octanoic) and capric (decanoic) acids. It is manufactured in USA.

Captex® 355 EP/NF is manufactured by the esterification of glycerin and fatty acids, mainly caprylic (‰ˆ55%) and capric. It contains not less than 95% of saturated fatty acids with 8 and 10 carbon atoms. It is prepared from raw materials of vegetable sources. It is miscible with most organic solvents including 96% ethanol. It is manufactured in USA.

Capmul® PG-12 EP/NF is a propylene glycol monoester of lauric acid. It is an excellent solubilizer for many complex poorly soluble drug compounds. Capmul® PG-12 EP/NF is used primarily as a carrier in soft and hard gelatin capsules, a penetration enhancer in transdermal drug delivery systems, and a secondary emulsifier in microemulsions. It is manufactured in USA.

Capmul® PG-2L EP/NF is a mixture of the propylene glycol mono- and diesters of lauric (dodecanoic) acid. It contains not less than 70.0 percent of diesters and not more than 30.0 percent of monoesters. Capmul® PG-2L EP/NF may be appropriate for microemulsions, soft gelatin capsules, suppositories, suspensions, and/or topical applications. It is manufactured in USA.

Acconon® C-44 EP/NF is a mixture of monoesters, diesters, and triesters of glycerol and monoesters and diesters of polyethylene glycols with a mean relative molecular mass of 1500. It may contain free macrogols. It is manufactured in USA.

Capmul® PG-8 NF is Type II Propylene Glycol Monocaprylate, a propylene glycol monoester of caprylic acid. It is an excellent solvent and a good bioavailability enhancer for many complex, poorly soluble drug compounds. Capmul® PG-8 NF is used primarily as a carrier in soft and hard gelatin capsules and a penetration enhancer in transdermal drug delivery systems. It is manufactured in USA.

CAPMUL® MCM NF is a mixture of monoacylglycerols, obtained by direct esterification of glycerol with caprylic (octanoic) and capric (decanoic) acids. It is manufactured in USA.

Capmul® GDB EP/NF is a mixture of diglycerides, mainly glyceryl dibehenate, together with variable quantities of monoglycerides and triglycerides. It is obtained by the esterification of glycerol with behenic acid of vegetable origin. It is manufactured in USA.

Stearoyl macrogolglycerides are mixtures of monoesters, diesters and triesters of glycerol and monoesters and diesters of macrogols (polyethylene glycols (PEG) with a mean relative molecular mass between 300 and 4000). They are obtained by partial alcoholysis of saturated oils containing mainly triglycerides of stearic acid using macrogol (PEG) or by esterification of glycerol and macrogol (PEG) with saturated fatty acids or by mixture of glycerol esters and condensates of ethylene oxide with the fatty acids of these hydrogenated oils. The product may contain free polyethylene glycols, and appears as a pale-yellow, waxy solid. It is manufactured in USA.

Captex® 355 EP/NF/JPE is manufactured by the esterification of glycerin and fatty acids, mainly caprylic (‰ˆ55%) and capric. It contains not less than 95% of saturated fatty acids with 8 and 10 carbon atoms. It is prepared from raw materials of vegetable sources. It is manufactured in USA.

Capmul® 808G EP/NF is a glycerin monoester of caprylic acid. It is a distilled monoester. It is manufactured in USA.

Captex® 200P is propylene glycol diesters of saturated fatty acids, mainly of caprylic and capric acids of vegetable origin. The low viscosity, excellent lubricity, and relatively non-oily character of Captex® 200P makes it ideally suited for a variety of pharmaceutical and clinical nutritional applications, including microemulsions, soft-gelatin capsules, suspensions, and suppositories. It is manufactured in USA.

Capmul® PG-8-70 NF is Type I Propylene Glycol Monocaprylate, a propylene glycol monoester of caprylic acid. It is an excellent solvent and a good bioavailability enhancer for many complex, poorly soluble drug compounds. Capmul® PG-8-70 NF is used primarily as a carrier in soft and hard gelatin capsules and a penetration enhancer in transdermal drug delivery systems. It is manufactured in USA.

Captex® 300 EP/NF is manufactured by the esterification of glycerin and fatty acids, mainly caprylic (‰ˆ70%) and capric. It contains not less than 95% of saturated fatty acids with 8 and 10 carbon atoms. It is prepared from raw materials of vegetable sources. It is miscible with most organic solvents including 96% ethanol. It is manufactured in USA.

Sunflower TPGS™ Pharmaceutical Grade Pharmaceutical Grade is the only commercially available non-GMO TPGS. It is produced exclusively from natural vitamin E derived from sunflower oil.

Antares TPGS Pharmaceutical Grade is a powerful tool in the formulation of poorly-soluble, lipophilic compounds and the enhancement of their absorption and bioavailability. Vitamin E TPGS is a water-soluble derivative of natural Vitamin E, which is formed by esterification of Vitamin E succinate with polyethylene glycol (PEG).

Sunflower TPGS™ Food Grade is the only commercially available non-GMO TPGS. It is produced exclusively from natural vitamin E derived from sunflower oil.

Vitamin ETPGS (NF Grade) is a water soluble form of Vitamin E suitable for nutraceutical, pharmaceutical and personal care from a natural source. Vitamin E Tocopheryl Polyethylene Glycol Succinate (TPGS) is widely used as an excipient in drug formulations and is rapidly expanding into the beverage and functional food markets. Structure - property relationship suggests that it uniquely meets the need for enhancing drug solubility, permeability, safety and enhancing the bioavailability.

Antares TPGS Food Grade is a powerful tool in the formulation of poorly-soluble, lipophilic compounds and the enhancement of their absorption and bioavailability. Vitamin E TPGS is a water-soluble derivative of natural Vitamin E, which is formed by esterification of Vitamin E succinate with polyethylene glycol (PEG).

Waglinol 3/9280.00 is a Waglinol emollient esters that are suitable for formulating creams, lotions, and ointments. Liquid esters are especially useful as delivery vehicles of lipophilic actives while solid wax esters are used as carriers in capsule filling, also act as surface treatment and binder in tablets.

DUBCARE OE is Liquid ethyl oleate with excellent spreading properties. Compliance with EP and USP. Suitable for topical applications.

Shanghai Qifuqing Material Technology Povidone Iodine PVP-I is a loose complex formed by the combination of elemental iodine and a polymer carrier. Povidone iodine acts as a carrier and solubilizing agent. It is yellow-brown to brown-red amorphous powder at room temperature.

STELLIESTERS 810 PG is Liquid diesters of caprylic and capric acid and propylene glycol alcohols with excellent spreading properties. Complies with EP and USP. Suitable for topical applications.Recommend using STELLIESTERS 810 PG in combination with STELLIESTERS LIQUIDE

STELLIESTERS IPM is Ester of myristic and isopropylic alcohol. Oily liquid complies with EP & USP and is suitable for topical applications.Recommend using STELLIESTERS IPM in combination with DUBCARE OD.

INNOSTEAM GMBH Glycerine is produced by the saponification or transesterification of vegetable fats and can be used in many different areas such as cosmetics, medicine, agriculture or as a basis for the production of e-liquids.