Products in Pharmaceutical Manufacturing: Binder

NUTRIOSE® FM06 Dextrin can be used to add dietary fiber to capsules, films, granules, lozenges and other pharmaceutical applications. Benefits BSE-free Gluten-free Halal and Kosher certified Melamine-free Non-GMO Non-Hazardous TSE-free Vegan Features Chemical stability Easy dispersability

XYLISORB® Xylitol powders are used in coatings for pharmaceutical and nutraceutical formulations, and as a filler, filler/binder and bulk sweetener that provides nutrient benefits. Applications Swallowable tablets Medicated confectionery Features Five-carbon polyol with a characteristic crystalline shape Low-calorie, sugar-free ingredient with high natural sweetness Suitable for use in formulations addressing pediatric and diabetic patient populations

NEOSORB® XTAB 300S is a directly compressible sorbitol powder that can be used for very hard, sugar-free tablets with high flavor load. Benefits Delivers a smooth, hard and uniform colored surface Provides a clean, cooling effect Does not produce acids or cause dental plaque or tooth decay Nutritional benefits (maintenance of tooth mineralization, tooth-friendly generic EU claims) recognized by European regulations Features Non-cariogenic Sugar-free

T-Det® PEG 4000 F is a water-soluble polymer made from ethylene oxide. It has a wide range of applications as a humectant and viscosity modifier in the cosmetic and personal care industries, a mold release agent and lubricant in the rubber industry, and a binder and dry lubricant for pill and tablet manufacture in the pharmaceutical industry.

MASCEROL™ Glycerine 99.7 USP, non-GMO, RSPO MB is highly refined with a minimum glycerol content of 99.7%. MASCEROL™ Refined Glycerine is used as a base ingredient in personal care preparations. It provides moisturizing properties and improves skin permeability. It is a gentle ingredient for anti-aging and anti-irritant cosmetics found in skin and hair care applications, shaving cream, soaps, and water-based lubricants. MASCEROL™ Refined Glycerine is used as an excipient in pharmaceutical production and preparations for improving smoothness, providing lubrication, and because of its humectant characteristics. It is also found in allergen immunotherapies, cough syrups, tinctures, elixirs, and expectorants. It is a tablet-holding agent and a key ingredient in soft gelatin capsules. In food as well as beverage applications, MASCEROL™ serves as a humectant or wetting agent, solvent, sweetener, or sugar substitute (approximately 60% as sweet as sucrose), thickening agent, or filler.

MASCEROL™ Glycerine 99.7 USP, non-GMO is highly refined with a minimum glycerol content of 99,7%. MASCEROL™ Refined Glycerine is used as a base ingredient in personal care preparations. It provides moisturizing properties and improves skin permeability. It is a gentle ingredient for anti-aging and anti-irritant cosmetics, found in skin & hair care applications, shaving cream, soaps & water-based lubricants. MASCEROL™ Refined Glycerine is used as an excipient in pharmaceutical production and preparations for improving smoothness, providing lubrication, and because of its humectant characteristics. It is found in allergen immunotherapies, cough syrups, tinctures, elixirs & expectorants. It is a tablet-holding agent and a key ingredient in soft gelatin capsules. In food as well as beverage applications MASCEROL™ serves as a humectant or wetting agent, solvent, sweetener or sugar substitute (approx. 60 % as sweet as sucrose), thickening agent, or filler.

METOLOSE® 65SH-1500 consists of methyl cellulose (USP, JP, EP) and three substitution types of hydroxypropyl methyl cellulose (hypromellose USP, JP, EP) each available in several grades differing in viscosity. METOLOSE® 65SH-1500 provides a variety of functions such as water retention, protective colloid, surface activity, sustained release. It is a non-ionic compound resistant to salting out and stable over a wide pH-range. Typical applications of METOLOSE® 65SH-1500 are binder for solid dosage forms such as tablets and granules or thickener for liquid applications.

METOLOSE® SM 4 consists of methyl cellulose (USP, JP, EP) and three substitution types of hydroxypropyl methyl cellulose (hypromellose USP, JP, EP) each available in several grades differing in viscosity.

METOLOSE® SM 100 consists of methyl cellulose (USP, JP, EP) and three substitution types of hydroxypropyl methyl cellulose (hypromellose USP, JP, EP) each available in several grades differing in viscosity.

METOLOSE® consists of methyl cellulose (USP, JP, EP) and three substitution types of hydroxypropyl methyl cellulose (hypromellose USP, JP, EP) . METOLOSE SB-4 is an excellent sugar coating binder for solid dosage forms.

METOLOSE® SM 25 consists of methyl cellulose (USP, JP, EP) and three substitution types of hydroxypropyl methyl cellulose (hypromellose USP, JP, EP) each available in several grades differing in viscosity.

METOLOSE® SM 15 consists of methyl cellulose (USP, JP, EP) and three substitution types of hydroxypropyl methyl cellulose (hypromellose USP, JP, EP) each available in several grades differing in viscosity.

TYLOPUR® is a versatile hypromellose, compliant with USP, JP, EP. TYLOPUR 60SH-13000 provides a genuine consistency in Sustained release (matrix tablets). It also can be used as thickener in aqeous solution .

METOLOSE® SM 4000 consists of methyl cellulose (USP, JP, EP) and three substitution types of hydroxypropyl methyl cellulose (hypromellose USP, JP, EP) each available in several grades differing in viscosity.

METOLOSE® SM 400 consists of methyl cellulose (USP, JP, EP) and three substitution types of hydroxypropyl methyl cellulose (hypromellose USP, JP, EP) each available in several grades differing in viscosity.

Capsules prepared from hypromellose have advantages in comparison with gelatin based capsules. Hypromellose capsules show a better moisture stability and are suitable for vegetarian/vegan patients. Low viscosity hypromellose products like METOLOSE 65SH-5 is suitable for capsule manufacturing.

METOLOSE® SM 1500 consists of methyl cellulose (USP, JP, EP) and three substitution types of hydroxypropyl methyl cellulose (hypromellose USP, JP, EP) each available in several grades differing in viscosity.

TYLOPUR Xtend Nutra® is a plant derived ingredient (high viscous hydroxypropyl methylcellulose, HPMC) that has been developed by Shin-Etsu to provide a controlled, extended release of active compounds over a longer period of time, prolonging their effects on human body. TYLOPUR Xtend Nutra® acts as a hydrophilic matrix agent in hydrophilic matrix system, which is the simplest sustained release technology, consisting essentially of an active compound and a water soluble highly viscous natural polymer. Such a system allows a simple and straight forward direct compression formulation and a reduction of doses per day. It is not only cost effective but it is also consumer friendly. The mechanism of action of TYLOPUR Xtend Nutra® in hydrophilic matrix tablets consists of initial swelling caused by the hydration of a tablet, protective gel formation, which regulates the degree of active compound’s release, and time-related extended release of an active compound through the gel layer.

TYLOPUR Xtend Nutra® is a plant derived ingredient (high viscous hydroxypropyl methylcellulose, HPMC) that has been developed by Shin-Etsu to provide a controlled, extended release of active compounds over a longer period of time, prolonging their effects on human body. TYLOPUR Xtend Nutra® acts as a hydrophilic matrix agent in hydrophilic matrix system, which is the simplest sustained release technology, consisting essentially of an active compound and a water soluble highly viscous natural polymer. Such a system allows a simple and straight forward direct compression formulation and a reduction of doses per day. It is not only cost effective but it is also consumer friendly. The mechanism of action of TYLOPUR Xtend Nutra® in hydrophilic matrix tablets consists of initial swelling caused by the hydration of a tablet, protective gel formation, which regulates the degree of active compound’s release, and time-related extended release of an active compound through the gel layer.

Tylopur ClearCoat Nutra® provides a multifunctional coating that not only provides brilliant, transparent and shiny finish to your nutraceutical tablets but additionally protects them against humidity and friability. Moreover, coating with Tylopur ClearCoat Nutra® improves tablets’ swallowability.

Tylopur ClearCoat Nutra® provides a multifunctional coating that not only provides brilliant, transparent and shiny finish to your nutraceutical tablets but additionally protects them against humidity and friability. Moreover, coating with Tylopur ClearCoat Nutra® improves tablets’ swallowability.

TYLOPUR® 605 is a versatile hypromellose, compliant with USP, JP, EP. It is a film coating material that provides an excellent finish.It is a effective binder, it does not interact with drugs.It also enhances the solubility of poorly solule APIs.

METOLOSE® 60SH-4000 is used as a sustained-release agent, thickener, suspending agent and binder for tablets and granules. It is lso used for ophthalmic formulations.

METOLOSE® 60SH-10000 is used as a sustained-release agent, thickener, suspending agent and binder for tablets and granules. It is lso used for ophthalmic formulations.

METOLOSE® 90SH-15000 is used as a sustained-release agent, thickener, suspending agent and binder for tablets and granules. It is lso used for ophthalmic formulations.

METOLOSE® SR 90SH-15000SR provides a genuine consistency in Sustained release (matrix tablets). It can be used for semi solid drug products.

PHARMACOAT® 603 is effective as a binder, since it does not interact with drugs. It has superior stability, a non-ionic character and is widely used as a binder for granulation. It is easy to use it as a film coating material that provides an excellent finish

METOLOSE® 65SH-4000 is used as a sustained-release agent, thickener, suspending agent and binder for tablets and granules. It is lso used for ophthalmic formulations.

METOLOSE® SR 90SH-4000SR provides a genuine consistency in Sustained release (matrix tablets). It can be used for semi solid drug products.

METOLOSE® 60SH-50 is used as a sustained-release agent, thickener, suspending agent and binder for tablets and granules. It is lso used for ophthalmic formulations.

METOLOSE® 90SH-4000 is used as a sustained-release agent, thickener, suspending agent and binder for tablets and granules. It is lso used for ophthalmic formulations.

METOLOSE® 65SH-50 is used as a sustained-release agent, thickener, suspending agent and binder for tablets and granules. It is lso used for ophthalmic formulations.

METOLOSE® 90SH-100000 is used as a sustained-release agent, thickener, suspending agent and binder for tablets and granules. It is lso used for ophthalmic formulations.

METOLOSE® SR 90SH-100SR provides a genuine consistency in Sustained release (matrix tablets). It can be used for semi solid drug products.

TYLOPUR® is a versatile hypromellose, compliant with USP, JP, EP. TYLOPUR® 60SH-50 provides a genuine consistency in Sustained release (matrix tablets). It also can be used as thickener in aqeous solution .It is also a good suspending agent in colloidal solution.