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BIOLIN/P

BIOLIN/P is a natural prebiotic that has been proven to help rebalance the skin’s microbiota. The prebiotics are based on inulin extracted from chicory root and they work by selectively supporting protective organisms to help restore the microbiota layer and prevent certain skin conditions. BIOLIN/P offers the benefit of barrier protection to both skin and scalp. It is a well-suited addition to a microbiome-based product. BIOLIN/P is a product from Gobiotics.

INCI Name: Alpha-Glucan Oligosaccharide, Inulin

Functions: Prebiotic, Protective Agent, Skin Barrier Protectant

Ingredient Origin: Natural Origin

Labeling Claims: Clean at Sephora, Credo Clean Standard, Natural, Naturally Derived, Ulta Beauty's Conscious Beauty

Benefit Claims: Barrier Function Improvement, Skin Barrier, Skin Microbiome, Skin Protection

Enhanced TDS

Knowde-enriched technical product data sheet

Identification & Functionality

INCI Name
Alpha-Glucan Oligosaccharide,
Inulin
Ingredient Origin
Natural Origin
Cosmetic Ingredients Functions
Prebiotic,
Protective Agent,
Skin Barrier Protectant
Technologies
Cosmetic Ingredients
Product Families
Cosmetic Ingredients — Cosmetic Actives
Skin Actives
Cosmetic Ingredients — Functionals
Conditioners & Emollients

Features & Benefits

Benefit Claims
Barrier Function Improvement,
Skin Barrier,
Skin Microbiome,
Skin Protection
Labeling Claims
Clean at Sephora,
Credo Clean Standard,
Natural,
Naturally Derived,
Ulta Beauty's Conscious Beauty
Key Benefits
  • Clinically proven to prevent reoccurrence of severe skin conditions
  • Reinforces the protective skin microbiota
  • Natural inulin and a-glucan-based prebiotic
  • Derived from chicory root, sugar beets and wheat
  • Selectively supporting beneficial organisms
  • Globally compliant (including China)

Applications & Uses

Markets
Personal Care
Applications
Personal Care — Beauty & Care
Skin Care
Use Level
0.5 – 3%
Formulation Guidelines
  • Recommended dosage: 0.5 – 3%
  • pH range: 4.3 – 10.0
  • Temperature: <60°C for durations up to 8 hours
  • Add to and dissolve in water phase
  • Can be dispersed in oil and esters
  • Prolonged and high temperature exposure can lead to slight yellowing
  • Avoid strong oxidizing agents (e.g. peroxides)
  • Avoid reducing agents

Properties

Physical Form
Powder,
Solid
Odor
Odorless
pH
4.3 – 10.0

Technical Details & Test Data

Combatting Recurrence of Severe Skin Conditions

Skin conditions are generally caused or sustained by microbiota imbalances characterized by dominance or infections by certain organisms, such as C. albicans, S. aureus, etc. The treatments for these conditions can be disruptive, leaving skin vulnerable for new infections due to the absence of a strong protective microbiota. BIOLIN/P can help restore the microbiota quickly and protect against new or reoccurring infections.

BIOLIN/P - Combatting Recurrence of Severe Skin Conditions

Clinical trial involving 15 atopic babies suffering from severe diaper rash caused by C. Albicans infection. Babies returned to hospital regularly for cortisone treatments. When using standard diaper rash creams afterwards the condition returned (left), whereas with application of same cream with 1.5% BIOLIN/P the condition did not reoccur (right). No conclusion is for a baby not brought back for evaluation.

 

Before Trial

BIOLIN/P - Combatting Recurrence of Severe Skin Conditions - 1

 

Evaluation after 1st and 2nd use peroid

BIOLIN/P - Combatting Recurrence of Severe Skin Conditions - 2

BIOLIN/P - Combatting Recurrence of Severe Skin Conditions - 3

Clinical trial involving 50 patients suffering from discomfort due C. Albicans infection. Use of 1.5% BIOLIN/P containing hygiene wash, 2 times 2-4 weeks use with 4-6 weeks rest period in-between. Dermatological and self-assessment shows no discomfort when using BIOLIN/P containing wash (right) compared to initial situation (left).

 

Increase in Hydration

BIOLIN/P - Combatting Recurrence of Severe Skin Conditions - 4

 

Decrease in TEWL

BIOLIN/P - Combatting Recurrence of Severe Skin Conditions - 5

Clinical trial involving 50 patients suffering from dry and irritated skin due to diabetic conditions, often characterized by C. Albicans and S. Aureus infections. 4 week application of cream combining benfothiamine and BIOLIN/P, showing overall improvement of skin health, including increased skin hydration, decreased TEWL and increased sebum content.