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JAKA (GREAF), a leading company specializing in R&D and production of efficacious active ingredients of cosmetics, is aiming at a global top cosmetic ingredients developer and manufacturer. We always focus on beautifying skin with advanced techniques, developing novel active ingredients and providing superior skincare solutions. 
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With an experienced technical team, JAKA is devoted to developing synthetic active ingredients, herbal extracts and fermentative ingredients in steps of global novel biotechnology. As a skincare solution expert and a leading local supplier of active ingredients, JAKA has been endeavoring to be at the forefront of international cosmetic industry and inspire the world with innovative technology.


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Gioactive

Gerbex



Gmoist® CS is a natural active raw material extracted from Capparis spinosa fruit. Growing in the harsh Gobi, C. spinosa (also known as "wild watermelon") has evolved a unique "noon break mode" that could respond to environmental changes intelligently. Its fruit is rich in alkaloids, sugars and glycosides, which can accurately act on the intelligent moisturizing pathway of the skin, leading to a strong moisturizing effect that help the skin deal with various environmental changes.


Gmoist

Redumatte

Gwhite

Gracest

Scalpatron VGP



Hairdian AP is a natural plant material developed for hair loss. The bioactive ingredients are extracted from Thuja orientalis, Zingiber officinale, Trifolium pratense and Artemisia argyi manufactured by two innovative techniques named ultrasonic-assisted semi bionic extraction and thermal infiltration integrated extraction. It focuses on the regulation of hair follicle cycle and could effectively reduce hair loss via promoting autophagy of dermal papilla cells (DPCs) and up-regulating the expression of some cell growth factors.


Hairdian

Comthing

Hairdian AP is a natural plant material developed for hair loss. The bioactive ingredients are extracted from Thuja orientalis, Zingiber officinale, Trifolium pratense and Artemisia argyi manufactured by two innovative techniques named ultrasonic-assisted semi bionic extraction and thermal infiltration integrated extraction. It focuses on the regulation of hair follicle cycle and could effectively reduce hair loss via promoting autophagy of dermal papilla cells (DPCs) and up-regulating the expression of some cell growth factors.

Hairdian AP

Gwhite® TAA is an internationally recognized skin whitening ingredient. It can prevent Melanin synthesis by inhibiting the key transcription factors of MITF, thus eliminating or reducing Chloasma(Chloasma is a disease caused by metabolic disorder of skin pigment) from the root. Meanwhile, Gwhite® TAA inhibits the synthesis of Interleukin and Prostaglandin, so it exhibits strong anti-inflammatory effects as well.

Gwhite® TAA

Gwhite® ABT is a whitening agent obtained by the chemical reaction of hydroquinone and glucose. It effectively improves the stability of hydroquinone and improves the biosafety. It can inhibit the activity of tyrosinase in skin cells, prevent the ormation of melanin, reduce the deposition of skin pigment, remove freckles, chloasma and pigmentation. It is a safe and effective whitening active ingredient popular in the market at present.

Gwhite® ABT

Urbluray™ MS is a fully restorative material from a natural plant source. The core ingredients come from Medicago sativa (Alfalfa) from Tibet, China. It is a safe and efficient anti blue light material, which can not only defense against blue light, but also repair the skin damage caused by blue light and UV.

Urbluray™ MS

Stephania tetrandra belongs to the Traditional Chinese Medicines, which was first recorded in "Shen Nong's Materia Medica". The main components of Stephania tetrandra are bisbenzylisoquinoline alkaloids, including tetrandrine, fangchinoline, etc.. Modern pharmacological studies have found that tetrandrine and its main components have a wide range of anti-inflammatory, antibacterial, and scar repairing effects.

Gerbex® Stepania

Honey is the nectar brewed by honeybee insects. It contains a variety of chemical components, such as sugars, acid compounds, flavonoids, proteins, vitamins, trace elements, etc. Its components are similar to the natural moisturizing factor (NMF) of human skin and have the effect of moisturizing. It also has anti-inflammatory, antibacterial, and antioxidant effects.

Biothex® Honey

Magnolia officinalis is the bark, root bark and branch bark of Magnolia officinalis and other plants of the Magnolia family. It is widely used in traditional Chinese medicine and Japanese Han medicine. "Shennong Materia Medica Classic" lists it as a top product and is mostly used to treat inflammation in clinic. Magnolol, the main active ingredient in the original medicinal materials, has been proved by previous studies to have anti-inflammatory, antibacterial, acne suppression and other pharmacological effects.

Gerbex® Magnolia

Gioactive® SPG-PF is beta-glucan fermented from Schizophyllum commune. Due to its water-soluble and electroneutral properties, Gioactive® SPG-PF is very suitable for cosmetic use. Gioactive® SPG-PF exhibits excellent anti-inflammation property and improves water content in Stratum Corneum effectively.

Gioactive® SPG-PF

Selaginella, a perennial herb, is the whole plant of Selaginella from the family Selaginellaceae, and it is also known as immortal grass. For growing in barren mountains and in dry rock seams, it’s extremely resistant to drought and cold. The main active ingredient in Selaginella is biflavonoids, which can inhibit acne-related inflammation and bacterial invasion by inhibiting the release of pro-inflammatory cytokines (iNOS and IL-1β, eliminating and inhibiting nitric oxide(NO), and inhibiting IL-1β and IL-8 Gene expression after acne bacillus inducing on cells. In addition, it has an anti-aging effect.

Gerbex® Selaginaella

Shanghai JAKA Biotech Co., Ltd.

JAKA (GREAF), a leading company specializing in R&amp;D and production of efficacious active ingredients of cosmetics, is aiming at a global top cosmetic ingredients developer and manufacturer. We alw

Shanghai JAKA Biotech Co., Ltd. - Knowde

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Anti-ROS® Triol is a classic natural antioxidant, which has many biological activities such as whitening, anti-aging, anti-inflammation and immune regulation. However, the instability and poor water solubility of resveratrol limit its applications in cosmetics. To overcome such disadvantages, JAKA develops an innovative type of resveratrol by using cyclodextrin wrapping technology, which greatly improves the stability and water solubility while maintaining its original biological activity.


Anti-ROS® Triol

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Ginkgo, also known as Ginkgo biloba, Duck‘s foot, Gongsun tree, etc., belongs to the gymnosperm Ginkgo family. It is the oldest plant in the existing seed plants. Currently, there is only one species of Ginkgo in this genus, other plants that are in the same genus with the ginkgo have already been extinct. Known as the "natural living fossil". Since ancient times, medicine and food are homologous and have extensive medicinal value. The main active ingredients of Ginkgo biloba are total flavonol glycosides, etc. Modern pharmacological studies have proved that it has whitening and anti-aging effects.

Gerbex® Ginkgo

Calmnerv™ CR is a natural plant source ingredient which can relieve the discomfort (stinging, itching, burning etc. ) of skin. It is extracted from green fruits of Citrus reticulata and contains various flavonoids and alkaloids. It could effectively inhibit the activation of TRPV1, and consequently reduce extracellular calcium influx, relieve discomforts of sensitive skin caused by different stimulus.

Calmnerv™ CR

Bletilla striata is a perennial herb of Orchidaceae, which belongs to Traditional Chinese Medicine. Its application in medicine goes back to ancient time in China. Bletilla striata has been a good medicine for facial beauty and is honored as "Whitening Fairy Maiden". The main component is the Bletilla striata polysaccharide, which has good hygroscopic ability and is often used as moisturizing agent. Bletilla striata also has the function of anti-oxidation, whitening and wound healing.

Gerbex® Bletilla

The traditional Chinese medicine Sophora flavescens is the root of Sophora, a plant of the genus Sophora. It is a traditional Chinese medicine with a long history in our country, which was first published in Shennong's Materia Medica. Modern research has shown that Sophora flavescens contains a large amount of alkaloids, which have anti-inflammatory and whitening effects.

Gerbex® Sophora

Gwhite® VCE has very stable chemical structure. It can be metabolized and play similar biological roles as Ascorbic Acid in vivo. Compared to Ascorbic Acid, Gwhite® VCE is lipophilic and hydrophilic, so it can enter Dermis more easily to exhibit biological effects on whitening.

Gwhite® VCE

Immedeline™ PG is a natural biopolymer that can bring instant tightening and lifting effect to skin. The core component is Prunus persica (Peach) resin from the Yulong Snow Mountain (also called the “Holy Mountain” in Yunnan Province). Immedeline™ PG brings skin visible tightening and lifting effect: tightening can be felt in 5 minutes and obvious wrinkles reduction could be observed in 10 minutes.

Immedeline™ PG

Paeonia suffruticosa is herb belonging to the Ranunculaceae. The bark of its root contains the active component Paeonol and is effective for whitening and anti-inflammation.

Gerbex® Suffruticosa

The Traditional Chinese Medicine Rhodiola crenulata is sourced from the root or rhizome of Rhodiola. Compendium of Materia Medica records that Rhodiola crenulata is "the best of the classic medicines, can dispel spiritual depression and make up for health deficiencies", which is "rare among known tonic medicines". The main active ingredient is salidroside, which has many skincare effects such as acne removal, anti-inflammation, whitening, oxidation resistance and light protection.

Gerbex® Rhodiola

Gioavtive® F-1000-PF is a biological polysaccharide derived from brown seaweeds, main component of which is Fucoidan. It is a new moisturizing agent, anti-wrinkle agent, skin recovering agent and skin conditioner in cosmetics industry. It improves the smoothness and softness of skin without increasing the viscosity.


Gioactive® F-1000-PF

Rejutime® PTC is of mergence with two highly-effective anti-aging actives and exhibits effects based on “3 Dimension Anti-aging Theory”: 1st Layer, to accelerate Keratinocyte proliferation and stimulate Growth Factor TGF*-β; 2nd layer, to improve synthesis of 3 key proteins in DEJ**; 3rd layer, to repair Dermal reticulate structure. With 6-weeks application, Rejutime® PTC can rebuild a young skin innovatively by enlivening epidermis, rejuvenating DEJ and regenerating dermis.

Rejutime® PTC

Gmoist® Sea-Gel-H is a novel moisturizing agent derived from marine plant Fucus Algae. It exhibits effects of regulating the formation of cornified envelope, repairing the skin barrier to resist cell drying and bringing a smooth and clean touch-feeling.

Gmoist® Sea-Gel-H

Redumatte® ECT is a small molecule derivative from amino acid, which is extracted from extremophiles. As an active ingredient with various cell-protecting functions, Redumatte® ECT has a simple mechanism of action and strong effects. It can protect skin cell from all damage elements, such as free radical, UV, PM pollution, hot temperature, coldness, etc., and keep skin healthy with moisturizing and anti-inflammation action.

Redumatte® ECT

Gwhite® PT40 PG is a solution of Glycyrrhiza glabra (Licorice) root extract and is an efficient whitening cosmetic agent. Its main active component “Glabridin” can inhibit the activity of Tyrosinase, TRP2 and DHICA oxidase, exhibit strong antioxidative effect, and effectively scavenge free radicals.

Gwhite® PT40 PG

Gwhite® α-ABT is a natural whitening agent, which is produced by the biological fermentation of glucose and hydroquinone under the action of glycosyltransferase. It is different from the common β-arbutin in configuration, so it has higher safety and efficacy. It can inhibit the activity of tyrosinase in skin cells, prevent the formation of melanin, reduce the deposition of skin pigment, remove freckles, chloasma and pigmentation. It is a very popular natural whitening active ingredient in the market at present.

Gwhite® α-ABT

Biothex® Ganoderma-H lucidum is a fungus belonging to the Polyporaceae. The active component Ganoderma lucidum Polysaccharides enables it to exhibit antioxidative and anti-wrinkle effects.

Biothex® Ganoderma-H

Olea europaea (Olive) is an evergreen tree belonging to Luteoceros family, mainly distributed in the Mediterranean region. Olive leaves have been used as Mediterranean folk medicine for thousands of years. The main active ingredients in olive leaves is oleuropein, which has antibacterial, anti-inflammatory, anti-oxidation and many other effects.

Gerbex® Olive

Aloe barbadensis has a long medicinal history, dating back to ancient Greece in the fourth century BC, Cleopatra in the first century BC used aloe as a regular beauty product.The main active ingredient of aloe is acemannan which has the functions of moisturizing and antioxidant.

Gerbex® Aloe-H

Antisebum® GMP is a safe and brand-new anti-acne ingredient with combinative function: anti-sebum, anti-keratinization, anti-bacteria and anti-inflammation. Antisebum® GMP is extracted from 3 classical vegetation skin: Garcinia mangostanacan, Magnolia officinalis and Punica granatum. It solves acne problems caused by hyperkeratinization or excessive sebum secretion, inhibits p.acnes viability and relieves skin irritation arising by P.acnes.


Antisebum® GMP

Polygonatum odoratum is the rhizome of Polygonatum, a plant of the genus Polygonatum in the Liliaceae. It was first published in Famous Doctors Records under the name "Fruinaceae". Polygonatum odoratum extract contains sugars, steroidal saponins and other substances. Polygonatum odoratum has good effects in moisturizing, anti-photo aging, and anti-oxidation.

Gerbex® Polygonatum

Polygonum cuspidatum is a commonly used Chinese medicinal material in clinical practice. It is the dried rhizome and root of the perennial herbaceous Cuspidatum in the Polygonaceae family. Cuspidatum was firstly recorded as medicine in "Famous Physician". It has a long history of medicinal use and has the effect of curing blood stasis and relieving pain. Its main active ingredients are polydatin and resveratrol, with antioxidant, anti-inflammatory and whitening effects.

Gerbex® Cuspidatum

Slimauty® CARN is a kind of alkaloid widely distributed in various human organs and connected to fat metabolism. It can promote the oxidation of Aliphatic acid in Mitochondria, thus expediting the metabolism of fat. In cosmetics, Slimauty® CARN exhibits a quick body slimming effect.

Slimauty® CARN

Excutin® 4MSK is a new and safe multifunctional cosmetic active ingredient. It inhibits the activity of Tyrosinase and prevents Melanin production, thereby reduces skin pigmentation. Excutin® 4MSK also significantly refrains the UV-induced Loricrin(Loricrin is a vital protein that promotes the normal shedding of Stratum Corneum, it can accelerate the terminal production of Keratinocyte and the formation of skin barrier), therefore it expedites the normal shedding of the Stratum Corneum which carries Melanin.

Excutin® 4MSK

Scalpatron VGP® is a novel active ingredient developed specially for protecting scalp mildly and relieving scalp itching, which extracted from 3 natural plants: Vitex trifolia, Gentiana scabra, Polygonum multifloru m. Their extracts exhibit potent efficacy of inhibiting secretion of Inflammation mediators, protect scalp from lipid peroxide’s irritation and solve scalp itching issue originally.

Scalpatron VGP®

Ophiopogon japonicus is the dried root tuber of Ophiopogon, a plant belonging to the genus Liliaceae. It is a commonly used Chinese medicine in clinical practice. It was first published in "Shen Nong's Materia Medica" and listed as the top grade. Ophiopogon root contains a variety of saponins, polysaccharides, flavonoids. Ophiopogon polysaccharides show good effects in moisturizing, anti-oxidation, and reduce the reactivity of ultraviolet radiation on skin damage.

Gerbex® Ophiopogon

Solarepare MB is a natural active raw material extracted from Magnolia biondii flower. M. biondii is produced in the genuine producing area, Nanzhao County, Henan Province. Its flowers are rich in lignans, which can effectively reduce the number of sunburned cells induced by ultraviolet (UV), reduce the reactivity of skin cells and blood vessels, improve skin structure and erythema, and alleviate UV damage.

Solarepare MB

Gmoist® HEU is a super cosmetic softener and moisturizer with strong hydroscopicity and water retaining capacity. It can improve the after-use skin feel, reduce the usage of conditioning agent, increase product’s stability in freezing-melting circulation as well as synergisticly moisturize skin. Besides, Gmoist® HEU is neither sticky nor greasy and has a broad pH adaptability. Experiments show that the combination of Gmoist® HEU and Glycerin could achieve better moisturizing effects.

Gmoist® HEU

White peony is the root of Paeonia lactiflora, a perennial herbaceous plant of Family Buttercup. White peony is a well-known Traditioncal Chinese Medicine with a long history of medicinal application and has the effect of facial beauty. The main active ingredient is paeoniflorin, which has the effect of anti-inflammation and whitening.

Gerbex® White Penoy

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