OraRez® W MA – Diacid

OraRez® W MA – Diacid is an outstanding mucoadhesiving showing the ability to complex, solubilize and retain actives on the mucosal tissue. The material’s bioadhesive properties’ and unique structure makes it an invaluable component to pharmaceutical products.

Brand: OraRez (10 products)

Chemical Name: Poly(Methylvinyl Ether-Co-Maleic Acid)

CAS Number: 25153-40-6

Functions: Chelating Agent, Controlled Release Agent, Film Former, Mucoadhesive, Solubilizer

Dosage Form: Transdermal Patches

Synonyms: Maleic acid-methoxyethylene copolymer, Maleic acid-methyl vinyl ether copolymer, Maleic acid-methyl vinyl ether polymer, Maleic acid-vinyl methyl ether copolymer, Methoxyethylene-maleic acid copolymer, Methyl vinyl ether-maleic acid copolymer, Methyl vinyl ether-maleic acid polymer, Poly(maleic acid-methyl vinyl ether), Poly(methyl vinyl ether-maleic acid), Vinyl methyl ether-maleic acid copolymer

Enhanced TDS

Knowde-enriched technical product data sheet

Identification & Functionality

Chemical Name: Poly(Methylvinyl Ether-Co-Maleic Acid)
Pharma & Nutraceuticals Functions: Chelating Agent,
Controlled Release Agent,
Film Former,
Mucoadhesive,
Solubilizer
CAS No.: 25153-40-6
EC No.: 607-572-6
Technologies: Pharmaceuticals & Nutraceuticals
Product Families: Pharmaceuticals & Nutraceuticals — Excipients
Formulation & Processing Aids,
Modified & Controlled Release,
Other Excipients,
Pharmaceutical Coatings,
Solvents & Solubilizers

Features & Benefits

Product Highlights

Biocompatible water-soluble film former.
Excellent bioadhesive/mucoadhesive properties.
Excellent chelating properties.
Enhances solubilization and retention of actives and drugs.
Broad molecular weight range and tunable rheology.
Polyanion having two distinct pKa’s.

Applications & Uses

Markets

Healthcare & Pharma

Applications

Healthcare & Pharma — Drug Delivery & Care Solutions

Dosage Form

Transdermal Patches

Recommended Uses and Known Applications

Retention of drugs on mucosal tissue.
Water-soluble, pain-free adhesive applications (e.g. ostomy bags, buccal patchs).
Solubilization/retention of actives in the oral cavity.
PVM/MA-polymer or PVM/MA-drug complex systems for controlled release.
Enteric coatings and systems.
Hydrogel dressing.

Properties

Soluble in: Water