Telangyn™ peptide solution

• Telangyn™ peptide fights the undesired effects caused by inflammation such as skin redness and dilated blood vessels, tissue degradation as well as post-inflammatory hyperpigmentation and dull skin.
• Inhibition of the inflammatory effect of LL-37
• Decrease of skin erythema
• Improvement of skin redness disorders
• Anti-collagenase Assay

Science

In the natural response of the immune system to potential harmful agents and conditions, kallikreins and antimicrobial compounds like cathelicidins have an important role. They induce the release of interleukines (ILs), which are among the increased molecules in facial skin redness and vascular alterations. In skin disorders with erythema and dilated blood vessels, like rosacea, LL-37 expression is found to be abnormally high, it is locally activated and a cascade of inflammatory reactions leads to an increase of pro-inflammatory metabolites, IL-6 and IL-8 among others.

The dermal connective tissue may be damaged as the proteolytic degradation of the extracellular matrix (ECM), mainly of collagen, is increased due to matrix metalloproteinases (MMPs) activation. Therefore, red areas become more visible as capillaries are fragile and permeable, and blood vessels can easily dilate due to inflammation. telangyn™ peptide helps to decrease facial redness and other skin disorders caused by LL-37 activation and subsequent release of ILs. It also provides a photoprotective effect lowering cell damage and skin inflammation negative effects.