Cellynkage™ marine ingredient

• Increased in vitro connexins levels
• Both direct and crosstalk are enhanced
• Improved appearance of menopausal skin

Science

• Skin cells are constantly exchanging signals to maintain proper function. A slowdown in this exchange rate occurs with age, resulting in missed communications that can lead to loss of tissue efficiency. Connexins (Cx) are transmembrane proteins that form specific intercellular channels known as gap junctions. They allow the passage of signals between cells that are in direct contact with each other and also among epidermal and dermal cells by facilitating the connection through information carriers, such as exosomes.
• Communication is key to controlling vital metabolic processes involved in keratinocyte growth, differentiation, homeostasis and morphogenesis. However, Cx levels are lost in mature skin, especially after menopause.
• Cellynkage™ marine ingredient enhances the levels of Cx in vitro, which are key to improve direct and paracrine communication. On menopausal women, a better skin thickness, dermal density and microrelief structure were measured, for an overall rejuvenated complexion.

Cellynkage™ marine ingredient can be incorporated into any cosmetic formulation that is intended to improve the appearance of sudden skin deterioration common in menopausal skin. Moreover, it can also be used in regular anti-aging products for rejuvenated appearance of mature skin.