Best Amino™ L-Isoleucine

Next limiting amino acid

• Isoleucine, together with Valine, is generally considered as the next limiting amino acids in monogastric animal diets.

Optimizing growth performance

• BCAAs are key amino acids for protein synthesis. Isoleucine optimizes the growth performance of animals by balancing BCAA in the feed.

Saving feed cost

• Isoleucine helps save feed costs by enabling reducing the use of expensive protein sources such as SBM.

Reducing N-excretion

• Low protein feeds reduce nitrogen excretion by increasing feed nitrogen utilization.

Feed Intake And Protein Synthesis

• The supply of sufficient isoleucine is of great importance, as insufficient supply of BCAA activates GCN2 expression which results in reduced-feed intake and protein synthesis. Also, BCAA increases protein synthesis by activating mRNA expression Level.

Gut Health / Immunity

• BCAA increases expression of amino acid transporter in intestines, influencing intestinal functions. Isoleucine enhances immunity by increasing the expression of B-defensin, and production of e-NOS ſendothelial nitric oxide synthase), thereby immune system.

Nursery Performance

• Isoleucine enhances growth of mammary cells and fetal development through mTOR signaling pathway and expression of IGF-1 and 2 in fetal liver. Sows consume BCAA to synthesize Glutamate, Aspartate and Glutamine and increase milk protein content.

Improving Energy Efficiency

• Isoleucine increases glucose uptake and energy efficiency in intestine and muscle by the expression of intestinal and muscular glucose transporters.