Bonolive®

Bonolive® is a patented olive leaf extract designed to support post-menopausal women and address concerns such as loss of bone mass, joint discomfort, and blood lipids disbalance.



Bonolive® is standardized for highly bioavailable oleuropein (>40%), a powerful phytonutrient unique to the olive tree.



At the cellular level, Bonolive® promotes bone formation by inhibiting adipocyte differentiation and enhancing differentiation into osteoblasts, the bone-building cells.



Additionally, Bonolive® reduces levels of inflammation and cartilage degradation biomarkers, such as PGE-2 and collagen-II, that are involved in the process.



Three clinical studies support bonolive® efficacy. A daily dose of 250 mg of Bonolive® results in the following health benefits:



  • Increases bone metabolism biomarker osteocalcin by 32%
  • Protects against loss of bone mass density
  • Reduces joint pain
  • Improves joints mobility
  • Improves blood lipid profile



Bonolive® is water-soluble and has shown excellent bioavailability in humans. It can be formulated in various dietary supplement forms, including capsules, sachets, tablets, chewable, gummies, shots and shelf-stable drinks.



Key applications:



  • Post-menopausal women's health
  • Osteopenia, osteoporosis, and bone health support
  • Osteoarthritis and joint health

Brand: Bonolive (1 products)

Ingredient Name: Olive Leaf Extract

Active Component: Oleuropein

Functions: Phytochemical

Physical Form: Powder, Solid

Benefit Claims (Health): Joint Support, Pain Reduction, Supports Menopause Health

Features: Excellent Bioavailability, Improved Bone Health, Promotes Joint Comfort And Mobility, Supports Healthy Joints

Enhanced TDS

Knowde-enriched technical product data sheet

Identification & Functionality

Features & Benefits

Applications & Uses

Properties

Physical Form
Appearance
Green to brown powder
Typical Properties
ValueUnitsTest Method / Conditions
Extraction SolventWater/Alcohol--
Raw Material/Extract Ratio12-15 : 1--
Polycyclic Aromatic Hydrocarbons (PAH)
ValueUnitsTest Method / Conditions
Benzo(a)Pyrenemax. 10ppb-
Sum of Benzo(a)Pyrene, Benz(a)Anthracene, Benzo(B)Fluoranthene and Chrysenemax. 50ppb-
Additional Information
ValueUnitsTest Method / Conditions
Pesticides**According To Regulation EC (396/2005)--
Ethylene Oxidemax. 0.02ppm-
Physico-Chemical Properties
ValueUnitsTest Method / Conditions
Loss on Dryingmax. 8.0%-
Residue By Calcinationmax. 9.0%-
Microbiological Values
ValueUnitsTest Method / Conditions
Total Plate Countmax. 10^{3}cfu/g-
Yeast & Moldmax. 10^{2}cfu/g-
Enterobacteriaceaemax. 10^{2}cfu/g-
SalmonellaAbsence/25g-
Escherichia ColiAbsence/g-
Staphylococcus AureusAbsence/g-
ColiformsAbsence/g-
Nutritional Information
ValueUnitsTest Method / Conditions
Nutritional Value (Calculated)381.3kCal/100g-
Total Fat Content0.3g/100g-
Saturated Fatty Acids56.4%-
Total Carbohydrates94.4g/100g-
Assimilable Carbohydrates93.1g/100g-
Total Sugar (As Glucose)4.2g/100g-
Total Fibers1.3g/100g-
Total Protein0.9g/100g-
Sodium62.7mg/100g-
Assay
ValueUnitsTest Method / Conditions
Polyphenolsmin. 50%HPLC (Internal method)
Oleuropeinmin. 40%HPLC (Internal method)
Verbascosidemin. 0.5%HPLC (Internal method)
Residual Solvents
ValueUnitsTest Method / Conditions
Residual SolventsEthanol And Water--
Heavy Metals
ValueUnitsTest Method / Conditions
Leadmax. 3ppm-
Cadmiummax. 1ppm-
Mercurymax. 0.1ppm-
Arsenicmax. 2.0ppm-
Note
  • *Analyzed at least one batch a year
  • ** Analyzed at raw material level
Solubility
Forms stable homogenous suspension when dispersed in water at 1 gram : 1 gram ratio

Regulatory & Compliance

Storage & Handling

Shelf Life
3 years
Storage & Shelf Life
  • Storage: Keep in tight containers to prevent dust formation. Store in a dry and cool place, away from direct sunlight. Keep away from ignition, heat, or electricity sources
  • Retesting date: 3 years after the date of production (when stored under the described conditions)