Enhanced TDS
Knowde-enriched technical product data sheet
Identification & Functionality
- INCI Name
- Ingredient Origin
- Cosmetic Ingredients Functions
- CAS No.
- 84012-27-1
- Technologies
- Product Families
Features & Benefits
- Benefit Claims
- Labeling Claims
- Product Highlights
- Anti-inflammatory
- Restoration
- Regeneration
- Antioxidant
Applications & Uses
- Markets
- Applications
- Application Format
- Skin Care Applications
- Use Level
- 0.2 - 0.5
Properties
- Physical Form
- Appearance
- Powder
- Odor
- Neutral
- Typical Properties
Value Units Test Method / Conditions Maslinic Acid 60 % Oleanolic Acid 20 % - Physico-Chemical Properties
Value Units Test Method / Conditions Density 0.45 - 0.55 kg/L PNT - 008 pH (10% Solution, 25°C) 4 - 6 - PNT - 009 - Microbiological Values
Value Units Test Method / Conditions Total Plate Count max. 1000 cfu/g PNT - 005 Yeast & Mold Count max. 100 cfu/g PNT - 005 Coliforms Negative - PNT - 005 Staphylococcus Aureus Negative - PNT - 005 Salmonella Spp Negative - PNT - 005 - Heavy Metals
Value Units Test Method / Conditions Lead 0 - 0.09 mg/kg PNT - 010 Cadmium max. 0.01 mg/kg PNT - 010 Arsenic 0 - 0.1 mg/kg PNT - 010 Mercury 0 - 0.012 mg/kg PNT - 010
Technical Details & Test Data
- Anti Pollution Test
- HACAT cells were exposed to PM (pollution) with and without OLEANOLIC acid for 30 min and fresh media were changed for 24 hours.
- Results show that oleanolic acid PROTECTS skin from PM exposure (pollution) and REDUCES INFLAMMATION and WRINKLES
- Anti Inflammatory Test
Several compounds were evaluated for their ability to inhibit INFLAMMATORY gene EXPRESSION of chemically-induced skin inflammation. Ursolic Acid, OLEANOLIC Acid, Corosolic Acid and MASLINIC Acid.
All compounds had the ability to inhibit the expression of one or more inflammatory genes, however, MASLINIC acid and OLEANOLIC acid were more EFFECTIVE than the others. The results confirmed ANTI-INFLAMMATORY and CHEMIOPREVENTIVE activities of cancer.
- Epidermal Barrier Function Test
OLEANOLIC ACID induces the differentiation of KERATINOCYTES through the increase of PPAR-alpha activity in HACaT cells.
OLEANOLIC Acid improves the RECOVERY of the barrier function of epidemic permeability, as well as the increase of CERAMIDES in the epidermis after topical application.
The application of OLEANOLIC acid accelerates the REPAIR of the barrier at 6 hours.
- Hydration Test
To confirm the effects of OLEANOLIC ACID on normal HYDRATION of the skin, they were measured for 1 and 3 weeks, compared to ursolic acid. Hydration INCREASED in both.
- Collagen Synthesis Test
IN VITRO Results of the SYNTHESIS of COLLAGEN from OLEANOLIC acid compared to RETINOL as a positive control.