Proxel® MB4 Preservative

Proxel® MB4 Preservative is a solvent-free, zero VOC, broad spectrum preservative for the protection of industrial water-based products against spoilage from bacteria, yeasts and fungi. It is a dual active blend of 1,2-benzisothiazolin-3-one (BIT) and 2-methyl-4-isothiazolin-3-one (MIT) that has been specially formulated. The actual labeling requirements for the formulated product should however be discussed with your local Lonza representative.

Brand: Proxel (25 products)

Functions: Anti-Microbial Agent, Preservative

Chemical Family: Isothiazolinones

Certifications & Compliance: ISO 9001

Enhanced TDS

Knowde-enriched technical product data sheet

Identification & Functionality

Chemical Family
Chemical Name
CASE Ingredients Functions
Cleaning Ingredients Functions
Technologies
Product Families
Chemical Structure

Proxel® MB4 Preservative - Chemical Structure

Composition

An aqueous solution of 1,2-benzisothiazolin-3-one (BIT) and 2-methyl-4-isothiazolin-3-one (MIT)

Features & Benefits

Applications & Uses

Markets
Applications
Home Care Applications
Applications

The product is effective in polymer emulsions, paints, adhesives, pigment dispersions and household products.

Amount to Use

The concentration required to adequately preserve your product depends on several factors. These include the susceptibility of the system to microbiological degradation, the extent to which microorganisms can gain access, the species involved, pH, temperature, and length of time for which protection is required.

Results of initial studies indicate that a concentration of PROXEL™ MB4 Preservative in the range 0.1-0.3% should be sufficient for most applications. Since the effective concentration can be dependent on several factors it is recommended that a testing program can be undertaken to determine the most cost-effective dose for your application.

Testing should take into account chemical compatibility/stability, plant hygiene conditions, susceptibility of the product to contamination, and the typical organisms involved.

Properties

Physical Form
Typical Physical Properties
ValueUnitsTest Method / Conditions
pH Value (25°C)8.0 - 9.5--
Boiling Point100°C
Flash PointBoils without flashing
Density (at 25°C)1.02 - 1.03g/ml
Minimum Inhibitory Concentrations (MIC)

Table 1.

Micro-organism MIC (ppm)
Bacteria  
Alcaligenes faecalis IMI 358536 15
Bacillus subtilis NCTC 10400 40
Burkholderia cepacia NCIMB 13694 190
Enterobacter cloacae CIP 104674 470
Escherichia coli IMI 362054 220
Proteus vulgaris IMI 358534 110
Pseudomonas aeruginosa IMI 358539 435
Pseudomonas putida IMI 358533 310
Pseudomonas stutzeri NCIMB 11359 55
Staphylococcus aureus NCIMB 9518 80
Fungi  
Aureobasidium pullulans PRA FS/1 220
Cladosporium herbarum PRA FS/5 150
Yeasts  
Rhodotorula rubra NCTC 9449 440
Saccharomyces cerevisiae NCYC 87 875
Preservative Properties

This product is effective against a range of problem microorganisms some of which are listed in Table 1. Please note that Minimum Inhibitory Concentrations (MIC) do not represent effective in-use concentrations which should be discussed with your local Lonza representative.


PROXEL™ MB4 Preservative has a non-specific mode of action which means
that bacterial resistance is very unlikely to occur.

Compatibility

Avoid strong alkaline conditions, oxidizing agents, reducing agents, amimes and mercaptans

Regulatory & Compliance

Certifications & Compliance
Chemical Inventories
Total Quality

Lonza holds a number of ISO 9001 Quality Management registrations covering our product range. The scope of each registration is specific to the location or entity named on the Registration Certificate and our products are supplied to ISO 9001 Standards.

Regulatory Information

The components of PROXEL™ MB4 Preservative are in compliance with the following inventories:

  • EINECS (Europe)
  • TSCA (USA)
  • AICS (Australia)
  • ENCS (Japan)
  • DSL (Canada)
  • KECL (Korea)
  • PICCS (Philippines)
  • IECSC (China)

Safety & Health

Risk Assessment and Management

Lonza professionals have a wide expertise in the fields of Safety, Health and the Environment. Lonza Microbial Control is committed to and uses this expertise in understanding the suitability of PROXEL™ MB4 Preservative for specific applications

Health and Safety

The PROXEL™ MB4 Preservative Safety Data Sheet may be supplied upon request. It should be read and understood by all supervisory personnel and employees before using this product

Packaging & Availability

Country Availability
Regional Availability
  • Africa
  • China
  • Europe
  • India
  • Japan
  • Latin America
  • Middle East
  • North America
  • Oceania
  • South East Asia

Storage & Handling

Storage & Stability

Stable under normal conditions of storage down to 0°C. If frozen, allow to thaw and stir well before use.