company tower banner
Biocogent LLC Company Logo

Pleiotanicals® Volpura® EPO (R10125)

1 of 9 products in this brand
Pleiotanicals® Volpura® EPO (R10125) is a plant-derived active ingredient extracted from Echinacea purpurea, known for its abundance in various active compounds, notably fatty acid alkylamides. This ingredient demonstrates the ability to activate PPAR-γ, which serves as the master regulator of adipogenesis. Its benefits lie in enhancing fat production by stimulating the differentiation of pre-adipocytes into adipocytes. This property makes it suitable for incorporation into formulations targeting anti-wrinkle effects, particularly for addressing expression lines in the forehead and nasolabial fold areas. Additionally, it finds application in facial contouring, re-firming, and plumping regimens aimed at addressing age-related lipoatrophy.

INCI Name: Caprylic/Capric Triglyceride, Echinacea Purpurea Extract, Squalane

Ingredient Origin: Natural Origin, Plant Origin

Labeling Claims: Naturally Derived, Plant-Based, Preservative-free

Benefit Claims: Anti-Aging, Anti-Inflammatory, Anti-Sagging, Anti-Wrinkle, Calming, Compatibility, Fine Lines Reduction, Firming, Formula Stability, Healthy-Looking Skin, Improves Skin Elasticity, Plumping, Promotes Youthful Skin, Reduces Crow’s Feet, Rejuvenating, Skin Strengthening Effect, Smooths Wrinkles, Soothing, Suitable for Sensitive Skin, Volumizing, Wrinkle Prevention, Wrinkle Refinement

  • TypeDocument Name
View All Documents

Knowde Enhanced TDS

Identification & Functionality

Cosmetic Ingredients Functions

Features & Benefits

Key Benefits

Benefit Claims:

  • Activates PPAR-γ, the master regulator of adipogenesis.
  • Increases fat production by stimulating pre-adipocyte differentiation into adipocytes.
  • Inhibits inflammation through the modulation of TNF-α and COX-2 activity.
  • Increased expression of six genes important for skin strength and health.

Clinical trial results showed:

  • Improvements of aging parameters in all three photographed areas: crow’s feet, nasolabial fold & forehead.
  • 44% increase in elasticity.
  • 14% increase in firmness.
  • Noticeable plumping effects on the face & back of the hands.
Compatibility Information
  • Volpura® EPO is compatible with most conventional ingredients used in skincare products.
  • Volpura® EPO has proven efficacy and stability in formulations requiring elevated temperatures up to 85°C for 6 hours.

Applications & Uses

Use Level
1 - 3 %
Applications
  • Volumizing and plumping formulas
  • Hot pour/hot cast products: Lipsticks, lip balms, lip glosses
  • Anti-wrinkle formulations for expression lines in the forehead and the nasolabial fold area
  • Facial contouring, re-firming, and plumping regimens to treat age-related lipoatrophy
  • Eye (peri-orbital lines) and lip contour products
  • Rejuvenating skin care products for neck and décolletage
  • Breast volumizing and buttocks sculpting formulations
  • Anti-aging hand creams
  • BB creams, CC creams, and color formulations
  • Soothing and calming for sensitive skin
  • Rejuvenating skin care products for neck and décolletage
  • Breast volumizing and buttocks sculpting formulations
  • Anti-aging hand creams
  • BB creams, CC creams, and color formulations
  • Soothing and calming for sensitive skin

Properties

Physical Form
Solubility
Appearance
Transparent liquid
Odor
Characteristic
Soluble in
Oil
Specifications
ValueUnitsTest Method / Conditions
Specific Gravity0.82 - 0.84--
Refractive Index1.44 - 1.46--

Technical Details & Test Data

Change in Appearance Comparison

Diminished appearance of facial wrinkles:

 - 2

Volpura® EPO is clinically proven to reduce the appearance of fine lines and wrinkles.

Heat Stability Comparison

Heat stability by alkylamide:

 - 1

Safety & Health

Safety Information
  • Human Repeat Insult Patch Testing (HRIPT) under semi-occlusive conditions indicated that Volpura® EPO is not a primary skin irritant or a primary skin sensitizer at recommended use levels.
  • Ocular irritation testing predicted that Volpura® EPO would be a Minimal ocular irritant at recommended use levels.

Storage & Handling

Shelf Life
12 months
Storage Conditions
  • Volpura® EP should be stored at room temperature in original packaging, protected from light.
  • Protect from extended cold storage and freezing.